NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex.
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DOI: 10.1002/advs.202504316
Abstract: The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual impairment. Current treatment outcomes remain limited. Investigating the role of the epigenetic long non‐coding RNA NEAT1 in TSC‐related epilepsy and cognition… read more here.
Keywords: tuberous sclerosis; neat1 knockdown; neat1 overexpression; sclerosis complex ... See more keywords
Electroacupuncture reduces neuroinflammation and neuronal pyroptosis via downregulating Neat1 in rats after stroke
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DOI: 10.1136/svn-2024-003964
Abstract: Background We investigated the potential contribution of the lncRNA Neat1 to the therapeutic efficacy of electroacupuncture (EA) after ischaemic stroke. Methods EA stimulation was used to treat cerebral ischaemia/reperfusion injury (CIRI) in the rat model.… read more here.
Keywords: electroacupuncture reduces; neuronal pyroptosis; neat1 overexpression; pyroptosis ... See more keywords