Effect of CYP2D6 Poor Metabolizer Phenotype on Stereoselective Nebivolol Pharmacokinetics.
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DOI: 10.2174/1872312812666180420104945
Abstract: BACKGROUND Nebivolol is a drug available as a racemate of d-nebivolol (SRRR) and lnebivolol (RSSS). In human liver microsomes, CYP2D6 mainly catalyses the metabolism of lnebivolol, while CYP2C19 catalyses the metabolism of d-nebivolol. Nebivolol stereoselective… read more here.
Keywords: phenotype; nebivolol pharmacokinetics; effect cyp2d6; cyp2d6 ... See more keywords