The Necessary Nitrogen Atom: A Versatile High-Impact Design Element for Multiparameter Optimization.
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DOI: 10.1021/acs.jmedchem.6b01807
Abstract: There is a continued desire in biomedical research to reduce the number and duration of design cycles required to optimize lead compounds into high-quality chemical probes or safe and efficacious drug candidates. The insightful application… read more here.
Keywords: necessary nitrogen; design; high impact; impact design ... See more keywords