Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1009927
Abstract: Regulated cell necrosis supports immune and anti-infectious strategies of the body; however, dysregulation of these processes drives pathological organ damage. Pseudomonas aeruginosa expresses a phospholipase, ExoU that triggers pathological host cell necrosis through a poorly… read more here.
Keywords: peroxidation; necrosis supports; cell necrosis; pathology ... See more keywords