Necrostatin-1 prevents skeletal muscle ischemia reperfusion injury by regulating Bok-mediated apoptosis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000806
Abstract: Background: Receptor interacting serine/threonine kinase 1 (RIPK1) mediates apoptosis by regulating the classic proapoptotic effectors Bcl-2-associated X protein (Bax) and Bcl-2 homologous antagonist/killer (Bak). Although Bcl-2-related ovarian killer (Bok) is structurally similar to Bak and… read more here.
Keywords: regulating bok; muscle; necrostatin; bok mediated ... See more keywords
Necrostatin‐1 mitigates renal ischaemia–reperfusion injury ‐ time dependent ‐ via aborting the interacting protein kinase (RIPK‐1)‐induced inflammatory immune response
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DOI: 10.1111/1440-1681.13625
Abstract: The recently defined necroptosis process participates in the pathophysiology of several tissue injuries. Targeting the necroptosis mediator receptor‐interacting protein kinase (RIPK1) by necrostatin‐1 in different phases of ischaemia–reperfusion injury (IRI) may provide new insight into… read more here.
Keywords: cell; reperfusion; necrostatin; ischaemia reperfusion ... See more keywords