A Case of Immune-Mediated Necrotizing Myopathy With Associated Skeletal Muscle Involvement by Sarcoid Granulomata: A Rare Association
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqz113.078
Abstract: Skeletal muscle involvement by noncaseating granulomata occurs in a variety of conditions, including sarcoidosis, infections, and rarely in association with primary inflammatory myopathies such as inclusion body myositis (IBM) and dermatomyositis (DM). Sarcoid myopathy is… read more here.
Keywords: skeletal muscle; muscle; necrotizing myopathy; association ... See more keywords
Cancer and immune-mediated necrotizing myopathy: A longitudinal referral case-controlled outcomes evaluation.
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DOI: 10.1093/rheumatology/keac144
Abstract: OBJECTIVES To investigate immune-mediated necrotizing myopathy (IMNM) association with cancer and its clinical implications. METHODS IMNM cases were identified January 1st, 2000 to December 31st, 2020 matching sex and age controls (4:1). RESULTS 152 patients… read more here.
Keywords: cancer; imnm diagnosis; fdg pet; immune mediated ... See more keywords
Immune-mediated necrotizing myopathy with anti-signal recognition particle antibodies, in a patient with melanoma treated with BRAF/MEK inhibitors.
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DOI: 10.1097/cmr.0000000000000831
Abstract: The effect of serine/threonine-protein kinase B-Raf/mitogen-activated protein kinase (BRAF/MEK) inhibitors on the immune system is not clearly described, but rare cases of autoimmune phenomena have been reported. The clinical case we present below is the… read more here.
Keywords: necrotizing myopathy; immune mediated; braf; mek inhibitors ... See more keywords
Anti-NXP2-antibody-positive immune-mediated necrotizing myopathy associated with acute myeloid leukemia
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DOI: 10.1097/md.0000000000011501
Abstract: Rationale: Idiopathic inflammatory myopathies have been extensively reported associated with malignancy. Immune-mediated necrotizing myopathy (IMNM), however, has rarely been connected with malignancy including acute myeloid leukemia (AML). Patient concerns: A 65-year-old woman was diagnosed with… read more here.
Keywords: necrotizing myopathy; mediated necrotizing; myeloid leukemia; anti nxp2 ... See more keywords
Severe necrotizing myopathy after COVID‐19 vaccine with BNT162b2 and regimen with ipilimumab plus nivolumab in a patient with advanced melanoma
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.17760
Abstract: Immune checkpoint inhibitors (ICIs) have dramatically changed the prognosis of advanced melanoma patients, but also exposed them to immune-related adverse events (irAEs).1 Furthermore, with the combination ipilimumab (IPI) plus nivolumab (NIVO) some rare irAEs, such… read more here.
Keywords: advanced melanoma; covid; plus nivolumab; severe necrotizing ... See more keywords
Association of immune‐mediated necrotizing myopathy with HLA polymorphisms
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DOI: 10.1111/tan.14950
Abstract: Immune‐mediated necrotizing myopathy (IMNM) is a type of autoimmune myositis typically characterized clinically by proximal muscle weakness with elevated creatine kinase levels, pathologically by myofiber necrosis and regeneration with paucity of lymphocytic cell infiltration, and… read more here.
Keywords: necrotizing myopathy; hla; immune mediated; mediated necrotizing ... See more keywords
Leflunomide-Induced Immune-Mediated Necrotizing Myopathy in a Patient With Rheumatoid Arthritis: A Case Report
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DOI: 10.1177/23247096221150636
Abstract: Immune-mediated necrotizing myopathy (IMNM) is a subtype of inflammatory myopathy that is characterized by proximal muscle weakness, markedly elevated serum creatine kinase, myopathic electromyographic findings, and muscle biopsies revealing necrosis or regeneration with sparse inflammatory… read more here.
Keywords: necrotizing myopathy; leflunomide; immune mediated; mediated necrotizing ... See more keywords
Characteristics of cardiac involvement in immune-mediated necrotizing myopathy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1094611
Abstract: Objective To investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM). Methods Patients diagnosed with Immune-mediated Necrotizing Myopathy (IMNM) who attended the Department of Neurology and the Department of Rheumatology and Immunology… read more here.
Keywords: necrotizing myopathy; immune mediated; involvement; mediated necrotizing ... See more keywords
Severe Recurrent Necrotizing Myopathy in Pregnancy: A Case Report
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DOI: 10.3389/fneur.2018.01028
Abstract: Pregnancy in patients with necrotizing autoimmune myopathy without identified antibodies is rarely reported. We report a case involving a 26-year-old woman with antibody-negative autoimmune necrotizing myopathy who experienced a relapse during pregnancy. Before pregnancy, the… read more here.
Keywords: pregnancy; necrotizing myopathy; case; report ... See more keywords
Pediatric immune-mediated necrotizing myopathy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1123380
Abstract: Immune-mediated necrotizing myopathy (IMNM) is a type of inflammatory myopathy. Most patients with IMNM produce anti-3-hydroxy-3-methylglutaryl coenzyme A reductase or anti-signal-recognition particle autoantibodies. IMNM is much rarer in children than in adults. We conducted this… read more here.
Keywords: pediatric imnm; immune mediated; necrotizing myopathy; mediated necrotizing ... See more keywords
Immune-Mediated Necrotizing Myopathy and Dietary Sources of Statins
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Internal Medicine"
DOI: 10.7326/l17-0620
Abstract: Background: Skeletal muscle diseases caused by autoimmune disorders are classified as idiopathic inflammatory myopathies. Muscle biopsy is used to divide these diseases into polymyositis, dermatomyositis, inclusion body myositis, nonspecific myositis, and immune-mediated necrotizing myopathy. Some… read more here.
Keywords: necrotizing myopathy; mediated necrotizing; statin; immune mediated ... See more keywords