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Published in 2018 at "Supportive Care in Cancer"
DOI: 10.1007/s00520-018-4052-1
Abstract: Ixazomib is a second-generation proteasome inhibitor that has been approved in the combination treatment of multiple myeloma and is currently under clinical investigation for the management of Waldenstrom’s macroglobulinemia. While cutaneous adverse events secondary to…
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Keywords:
ixazomib;
vasculitis;
induced cutaneous;
necrotizing vasculitis ... See more keywords
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Published in 2017 at "Nature Reviews Rheumatology"
DOI: 10.1038/nrrheum.2017.68
Abstract: Polyarteritis nodosa (PAN) is a vasculitic disease characterized primarily by necrotizing vasculitis — inflammatory lesions in blood vessels that lead to vessel wall necrosis. Our understanding of PAN and necrotizing vasculitis has evolved over time.…
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Keywords:
polyarteritis nodosa;
necrotizing vasculitis;
disease;
pan ... See more keywords
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Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.4570
Abstract: Background Systemic necrotizing vasculitis (SNV) is characterised by destructive and inflammatory changes in the vessels. Binding of autoantibodies and immune complexes on the surface of endothelial cells stimulates the synthesis of endothelin-1 (ET-1), which leads…
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Keywords:
kidney involvement;
vasculitis;
necrotizing vasculitis;
systemic necrotizing ... See more keywords