Sign Up to like & get
recommendations!
0
Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.088
Abstract: The class III phosphoinositide 3-kinase vacuolar protein sorting 34 (VPS34) is a core protein of autophagy initiation, yet the regulatory mechanisms responsible for its stringent control remain poorly understood. Here, we report that the E3…
read more here.
Keywords:
auto ubiquitination;
nedd4;
nedd4 recruits;
ubiquitination nedd4 ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17296
Abstract: Phosgene gas leakage can cause life‐threatening acute lung injury (ALI), which is characterized by inflammation, increased vascular permeability, pulmonary oedema and oxidative stress. Although the downregulation of neuronal precursor cell‐expressed developmentally downregulated 4 (NEDD4) is…
read more here.
Keywords:
lung;
phosgene induced;
nedd4;
lung injury ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.942769
Abstract: The human ether-á-go-go-related gene (hERG) encodes the pore-forming subunit (Kv11.1), conducting a rapidly delayed rectifier K+ current (I Kr). Reduction of I Kr in pathological cardiac hypertrophy (pCH) contributes to increased susceptibility to arrhythmias. However,…
read more here.
Keywords:
pch;
pathological cardiac;
nedd4;
cardiac hypertrophy ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.810473
Abstract: Serum and glucocorticoid-inducible kinase 3 (SGK3) is involved in maintaining podocyte function by regulating the protein levels of podocin and CD2-associated protein. Nephrin is also one of the slit diaphragm proteins of podocytes, but whether…
read more here.
Keywords:
nedd4;
sgk3;
kinase;
podocyte injury ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2021 at "International journal of molecular sciences"
DOI: 10.3390/ijms221910247
Abstract: BACKGROUND Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. It is highly resistant to chemotherapy, and tumor recurrence is common. Neuronal precursor cell-expressed developmentally downregulated 4-1 (NEDD4-1) is an E3 ligase…
read more here.
Keywords:
glioblastoma;
tmz resistant;
gbm cells;
nedd4 ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2017 at "Epilepsy Currents"
DOI: 10.5698/1535-7597.17.4.241
Abstract: Commentary Tightly regulated protein homeostasis is essential for neuronal function. In response to external stimuli, proteins are constantly added to and removed from synapses. The dynamic regulation of synaptic and neuronal protein content is achieved…
read more here.
Keywords:
protein;
epilepsy;
nedd4;
degrading seizures ... See more keywords