Articles with "neddylation cancer" as a keyword



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Targeting Protein Neddylation for Cancer Therapy.

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Published in 2020 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-15-1025-0_18

Abstract: Neddylation is a posttranslational modification that conjugates a ubiquitin-like protein NEDD8 to substrate proteins. The best-characterized substrates of neddylation are the cullin subunits of cullin-RING E3 ubiquitin ligase complexes (CRLs). CRLs as the largest family… read more here.

Keywords: neddylation cancer; targeting protein; protein neddylation; neddylation ... See more keywords