Neddylation-Independent Activities of MLN4924.
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DOI: 10.1007/978-981-15-1025-0_21
Abstract: MLN4924, also known as pevonedistat, is a highly selective small-molecule inhibitor of NEDD8 (neuronal precursor cell-expressed developmentally downregulated protein 8)-activating enzyme (NAE) to block the entire neddylation modification cascade, leading to inactivation of cullin-RING ligases… read more here.
Keywords: activities mln4924; independent activities; biology; neddylation independent ... See more keywords