Meta‐analysed numbers needed to treat of novel antidiabetic drugs for cardiovascular outcomes
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14213
Abstract: Absolute treatment effects—i.e. numbers needed to treat (NNTs)—of novel antidiabetic drugs for cardiovascular outcomes have not been comprehensively evaluated. We aimed to perform a meta‐analysis of digitalized individual patient outcomes to display and compare absolute… read more here.
Keywords: novel antidiabetic; antidiabetic drugs; numbers needed; drugs cardiovascular ... See more keywords
The number needed to treat adjusted for explanatory variables in regression and survival analysis: Theory and application
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in Medicine"
DOI: 10.1002/sim.9418
Abstract: The number needed to treat (NNT) is an efficacy index commonly used in randomized clinical trials. The NNT is the average number of treated patients for each undesirable patient outcome, for example, death, prevented by… read more here.
Keywords: explanatory variables; regression; number needed; needed treat ... See more keywords
The number needed to treat for net effect (NNTnet) as a metric for measuring combined benefits and harms.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of clinical epidemiology"
DOI: 10.1016/j.jclinepi.2020.05.031
Abstract: Calculating the number needed to treat (NNT) has been widely used to help understand treatment effect results of randomized controlled trials (RCTs). Combined benefit-and-harm profiles from RCT results have to be taken into account to… read more here.
Keywords: nntnet; effect; net effect; number needed ... See more keywords
Number needed to treat for direct oral anticoagulants over warfarin in atrial fibrillation.
Sign Up to like & getrecommendations! Published in 2017 at "Medicina clinica"
DOI: 10.1016/j.medcli.2017.03.039
Abstract: RE-LY2 Ensayo clínico 18.113 Dabigatrán 150 mg/12 h vs. warfarina 1,11 vs. 1 HR: 0,66 p < 0,001 Dabigatrán 110 mg/12 h vs. warfarina 1,53 vs. 1 HR: 0,91 p = 0,34 ROCKET-AF3 Ensayo clínico… read more here.
Keywords: dabigatr 150; ensayo nico; warfarina; 150 warfarina ... See more keywords
Lemborexant and Daridorexant for the Treatment of Insomnia: An Indirect Comparison, Using Number Needed to Treat, Number Needed to Harm, and Likelihood to Be Helped or Harmed
Sign Up to like & getrecommendations! Published in 2023 at "CNS Spectrums"
DOI: 10.1017/s1092852923002183
Abstract: Abstract Background To describe lemborexant and daridorexant for insomnia treatment using number needed to treat (NNT), number needed to harm (NNH), and likelihood to be helped or harmed (LHH). Methods Dichotomous outcomes were identified from… read more here.
Keywords: number needed; number; needed harm; using number ... See more keywords
Cost Needed to Treat (CNT) and Number Needed to Treat (NNT) analysis of drugs for treatment of heart failure in India
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.3539
Abstract: Only little attention has been paid to treatment strategies of chronic disease conditions that require long term treatment and repeated hospitalizations Our aim was to review cost-effectiveness of guideline directed medical therapy of heart failure… read more here.
Keywords: needed treat; cost; heart; heart failure ... See more keywords
0350 Daridorexant in patients with insomnia disorder: number needed to treat, number needed to harm & likelihood to be helped or harmed
Sign Up to like & getrecommendations! Published in 2023 at "SLEEP"
DOI: 10.1093/sleep/zsad077.0350
Abstract: Patients with insomnia disorder have difficulty initiating or maintaining sleep and have impaired daytime functioning. Daridorexant is a dual orexin receptor antagonist approved for the treatment of insomnia. This analysis reports the number needed to… read more here.
Keywords: number needed; number; patients insomnia; insomnia disorder ... See more keywords
Number (of Whom?) Needed to Treat (with What?): Exposures, Population Interventions, and the Number Needed to Treat.
Sign Up to like & getrecommendations! Published in 2019 at "Epidemiology"
DOI: 10.1097/ede.0000000000001061
Abstract: The number needed to treat (NNT) is a widely used measure of the potential impact of a treatment or intervention, but it is often calculated and discussed in ways which oversimplify critical issues. Specifically, the… read more here.
Keywords: number needed; treat exposures; exposures population; needed treat ... See more keywords
Utility of the number needed to treat in paediatric haematological cancer randomised controlled treatment trials: a systematic review
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Open"
DOI: 10.1136/bmjopen-2018-022839
Abstract: Objectives The primary objective was to assess the utility of the number needed to treat (NNT) to inform decision-making in the context of paediatric oncology and to calculate the NNT in all superiority, parallel, paediatric… read more here.
Keywords: utility number; number needed; cancer; needed treat ... See more keywords
Reduction in number to treat versus number needed to treat
Sign Up to like & getrecommendations! Published in 2021 at "BMC Medical Research Methodology"
DOI: 10.1186/s12874-021-01246-5
Abstract: Background We propose a new measure of treatment effect based on the expected reduction in the number of patients to treat (RNT) which is defined as the difference of the reciprocals of clinical measures of… read more here.
Keywords: treat; survival endpoints; number; reduction number ... See more keywords
Number-needed-to-treat analysis of clinical progression in patients with metastatic castration-resistant prostate cancer in the STRIVE and TERRAIN trials
Sign Up to like & getrecommendations! Published in 2018 at "BMC Urology"
DOI: 10.1186/s12894-018-0387-7
Abstract: BackgroundThis analysis estimated the number needed to treat with enzalutamide versus bicalutamide to achieve one additional patient with chemotherapy-naïve metastatic castration-resistant prostate cancer who would obtain clinical benefit regarding progression-free survival, radiographic progression-free survival, or… read more here.
Keywords: prostate; needed treat; metastatic castration; number needed ... See more keywords