Neferine induces mitochondrial dysfunction to exert anti-proliferative and anti-invasive activities on retinoblastoma
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370220928933
Abstract: Retinoblastoma is common primary intraocular malignancy of infants and childhood. Neferine is a major bisbenzylisoquinoline alkaloid derived from the lotus plumule in Nelumbo nucifera. This study evaluated the mitigation role of Neferine on retinoblastoma in… read more here.
Keywords: treatment significantly; retinoblastoma; neferine; neferine treatment ... See more keywords
Neferine alleviates ovalbumin-induced asthma via MAPK signaling pathways in mice.
Sign Up to like & getrecommendations! Published in 2023 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v51i3.840
Abstract: PURPOSE To investigate the role of neferine in ovalbumin (OVA)-induced asthma, and to reveal the possible mechanism. METHODS In OVA-induced asthmatic mice, enzyme-linked-immunosorbent serologic assay was performed to evaluate the level of interleukin (IL)-4, IL-5,… read more here.
Keywords: ova induced; mapk signaling; induced asthma; neferine ... See more keywords
Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00238
Abstract: Neferine, a bisbenzylisoquinoline alkaloid isolated from the green seed embryos of Lotus (Nelumbo nucifera Gaertn), has been previously shown to have various anti-cancer effects. In the present study, we evaluated the effect of neferine in… read more here.
Keywords: nelumbo nucifera; bisbenzylisoquinoline alkaloid; analyses neferine; neferine ... See more keywords
Anti-Adipogenic Effect of Neferine in 3T3-L1 Cells and Primary White Adipocytes
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DOI: 10.3390/nu12061858
Abstract: Neferine, an alkaloid component extracted from lotus seed embryos, is known for its anti-inflammatory, anticancer, and antioxidant properties. However, the anti-adipogenic activity of neferine has not been thoroughly investigated. In this study, neferine was found… read more here.
Keywords: effect neferine; anti adipogenic; neferine; neferine 3t3 ... See more keywords