Structural insights into the mechanism of a novel protein targeting pathway in Gram‐negative bacteria
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12813
Abstract: Many nascent polypeptides synthesized in the cytoplasm are translocated across membranes via a specific ‘translocon’ composed of protein complexes. Recently, a novel targeting pathway for the outer membrane β‐barrel proteins (OMPs) in Gram‐negative bacteria was… read more here.
Keywords: protein; mechanism; gram negative; negative bacteria ... See more keywords
Enhanced Nitric Oxide Delivery Through Self‐Assembling Nanoparticles for Eradicating Gram‐Negative Bacteria
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202403046
Abstract: In the current battle against antibiotic resistance, the resilience of Gram‐negative bacteria against traditional antibiotics is due not only to their protective outer membranes but also to mechanisms like efflux pumps and enzymatic degradation of… read more here.
Keywords: gram negative; delivery; negative bacteria; nitric oxide ... See more keywords
How bacterial cell division might cheat turgor pressure – a unified mechanism of septal division in Gram‐positive and Gram‐negative bacteria
Sign Up to like & getrecommendations! Published in 2017 at "BioEssays"
DOI: 10.1002/bies.201700045
Abstract: An important question for bacterial cell division is how the invaginating septum can overcome the turgor force generated by the high osmolarity of the cytoplasm. I suggest that it may not need to. Several studies… read more here.
Keywords: gram positive; gram; gram negative; division ... See more keywords
Expanding the Spectrum: Modified Bacteriocin Nisin as a Trojan Horse Against Gram‐Negative Salmonella Typhimurium and Escherichia coli
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology Journal"
DOI: 10.1002/biot.70019
Abstract: Nisin is an antimicrobial peptide widely used as a biopreservative to extend shelf life and control foodborne pathogens, particularly Gram‐positive bacteria such as Listeria monocytogenes. However, its efficacy against Gram‐negative bacteria is limited due to… read more here.
Keywords: gram negative; spectrum; coli; typhimurium escherichia ... See more keywords
Motuporamine Derivatives as Antimicrobial Agents and Antibiotic Enhancers against Resistant Gram‐Negative Bacteria
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DOI: 10.1002/cbic.201600532
Abstract: Dihydromotuporamine C and its derivatives were evaluated for their in vitro antimicrobial activities and antibiotic enhancement properties against Gram‐negative bacteria and clinical isolates. The mechanism of action of one of these derivatives, MOTU‐N44, was investigated against… read more here.
Keywords: motuporamine derivatives; agents antibiotic; antimicrobial agents; gram negative ... See more keywords
Identification of a 2‐Aminobenzimidazole Scaffold that Potentiates Gram‐Positive Selective Antibiotics Against Gram‐Negative Bacteria
Sign Up to like & getrecommendations! Published in 2024 at "ChemBioChem"
DOI: 10.1002/cbic.202400127
Abstract: The development of novel therapeutic approaches is crucial in the fight against multi‐drug resistant (MDR) bacteria, particularly gram‐negative species. Small molecule adjuvants that enhance the activity of otherwise gram‐positive selective antibiotics against gram‐negative bacteria have… read more here.
Keywords: gram negative; positive selective; gram positive; selective antibiotics ... See more keywords
Engineered Phages and Engineered and Recombinant Endolysins Against Carbapenem‐Resistant Gram‐Negative Bacteria: A Focused Review on Novel Antibacterial Strategies
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.70078
Abstract: Antibiotic resistance has escalated globally, affecting not only commonly used antibiotics but also last‐resort agents such as carbapenems and colistin. The rise of antibiotic‐resistant bacteria has prompted microbiologists to devise new strategies, with bacteriophages emerging… read more here.
Keywords: resistant gram; resistance; gram negative; negative bacteria ... See more keywords
Combined use of lipopolysaccharide-binding protein dsRNA and Gram-negative bacteria for pest management of Coptotermes formosanus.
Sign Up to like & getrecommendations! Published in 2023 at "Pest management science"
DOI: 10.1002/ps.7405
Abstract: BACKGROUND RNA interference (RNAi) technology is an environmentally friendly strategy for controlling insect pests. Lipopolysaccharide-binding protein (LBP) recognizes lipopolysaccharides, which are a major outer membrane constituent of Gram-negative bacteria. We propose that the LBP gene… read more here.
Keywords: binding protein; lipopolysaccharide binding; management; negative bacteria ... See more keywords
Bacteriological Assessment of Pneumonia Caused by Gram-Negative Bacteria in Patients Hospitalized in Intensive Care Unit.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2016_163
Abstract: The article presents the results of 11-year study (2005-2015) of Gram-negative bacteria responsible for pneumonia in 2033 mechanically ventilated patients hospitalized in Intensive Care Unit. Of 8796 biological samples, consisting mainly of bronchial aspirate (97.9 %),… read more here.
Keywords: gram negative; intensive care; negative bacteria; patients hospitalized ... See more keywords
A tridecaptin-based fluorescent probe for differential staining of Gram-negative bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1465-0
Abstract: The traditional Gram-staining method, which was invented more than a century ago for differentiating bacteria as Gram positive or Gram negative, is still widely practiced in microbiology. However, Gram staining suffers from several problems which… read more here.
Keywords: fluorescent probe; staining gram; probe; gram negative ... See more keywords
Quorum sensing between Gram-negative bacteria responsible for methane production in a complex waste sewage sludge consortium
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-9553-9
Abstract: Quorum sensing (QS) plays a key role in activating bacterial functions through small molecules called autoinducers. In this study, the QS of Gram-negative bacteria in waste sewage sludge (WSS) was downregulated by adding the quorum… read more here.
Keywords: quorum sensing; gram negative; methane production; negative bacteria ... See more keywords