Structural insights into the mechanism of a novel protein targeting pathway in Gram‐negative bacteria
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12813
Abstract: Many nascent polypeptides synthesized in the cytoplasm are translocated across membranes via a specific ‘translocon’ composed of protein complexes. Recently, a novel targeting pathway for the outer membrane β‐barrel proteins (OMPs) in Gram‐negative bacteria was… read more here.
Keywords: protein; mechanism; gram negative; negative bacteria ... See more keywords
How bacterial cell division might cheat turgor pressure – a unified mechanism of septal division in Gram‐positive and Gram‐negative bacteria
Sign Up to like & getrecommendations! Published in 2017 at "BioEssays"
DOI: 10.1002/bies.201700045
Abstract: An important question for bacterial cell division is how the invaginating septum can overcome the turgor force generated by the high osmolarity of the cytoplasm. I suggest that it may not need to. Several studies… read more here.
Keywords: gram positive; gram; gram negative; division ... See more keywords
Motuporamine Derivatives as Antimicrobial Agents and Antibiotic Enhancers against Resistant Gram‐Negative Bacteria
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DOI: 10.1002/cbic.201600532
Abstract: Dihydromotuporamine C and its derivatives were evaluated for their in vitro antimicrobial activities and antibiotic enhancement properties against Gram‐negative bacteria and clinical isolates. The mechanism of action of one of these derivatives, MOTU‐N44, was investigated against… read more here.
Keywords: motuporamine derivatives; agents antibiotic; antimicrobial agents; gram negative ... See more keywords
Combined use of lipopolysaccharide-binding protein dsRNA and Gram-negative bacteria for pest management of Coptotermes formosanus.
Sign Up to like & getrecommendations! Published in 2023 at "Pest management science"
DOI: 10.1002/ps.7405
Abstract: BACKGROUND RNA interference (RNAi) technology is an environmentally friendly strategy for controlling insect pests. Lipopolysaccharide-binding protein (LBP) recognizes lipopolysaccharides, which are a major outer membrane constituent of Gram-negative bacteria. We propose that the LBP gene… read more here.
Keywords: binding protein; lipopolysaccharide binding; management; negative bacteria ... See more keywords
Bacteriological Assessment of Pneumonia Caused by Gram-Negative Bacteria in Patients Hospitalized in Intensive Care Unit.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2016_163
Abstract: The article presents the results of 11-year study (2005-2015) of Gram-negative bacteria responsible for pneumonia in 2033 mechanically ventilated patients hospitalized in Intensive Care Unit. Of 8796 biological samples, consisting mainly of bronchial aspirate (97.9 %),… read more here.
Keywords: gram negative; intensive care; negative bacteria; patients hospitalized ... See more keywords
A tridecaptin-based fluorescent probe for differential staining of Gram-negative bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1465-0
Abstract: The traditional Gram-staining method, which was invented more than a century ago for differentiating bacteria as Gram positive or Gram negative, is still widely practiced in microbiology. However, Gram staining suffers from several problems which… read more here.
Keywords: fluorescent probe; staining gram; probe; gram negative ... See more keywords
Quorum sensing between Gram-negative bacteria responsible for methane production in a complex waste sewage sludge consortium
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-9553-9
Abstract: Quorum sensing (QS) plays a key role in activating bacterial functions through small molecules called autoinducers. In this study, the QS of Gram-negative bacteria in waste sewage sludge (WSS) was downregulated by adding the quorum… read more here.
Keywords: quorum sensing; gram negative; methane production; negative bacteria ... See more keywords
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2673-9
Abstract: The necessity to develop therapeutic agents and strategies to abate the spread of antibiotic-resistant pathogens is prominent. Antimicrobial peptides (AMPs) provide scaffolds and inspiration for antibiotic development. As an AMP of shorter scaffold, eight dilipid… read more here.
Keywords: gram negative; conventional antibiotics; negative bacteria; ultrashort cationic ... See more keywords
Molecular Insights into Compound-Transporter Interactions: The Case of Inhibitors of Gram-Negative Bacteria Efflux Pumps
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DOI: 10.1016/j.bpj.2016.11.1483
Abstract: The Escherichia coli AcrAB-TolC efflux pump is the archetype of the Resistance-Nodulation-cell Division (RND) exporters from Gram-negative bacteria. Overexpression of RND-type efflux pumps is a major factor in multidrug resistance (MDR), which makes these polyspecific… read more here.
Keywords: gram negative; compound transporter; negative bacteria; molecular insights ... See more keywords
Engineering the Cell Envelope of Gram-Negative Bacteria
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DOI: 10.1016/j.bpj.2016.11.1675
Abstract: The cell envelope in Gram-negative bacteria is made of two distinct membranes and a cell wall between them. Although there is growing interest in the mechanical adaptation of this cell envelope to turgor pressure, how… read more here.
Keywords: cell envelope; gram negative; envelope gram; negative bacteria ... See more keywords
Rational Design of New Antimicrobial Peptides Targeting Gram Negative Bacteria
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DOI: 10.1016/j.bpj.2016.11.2098
Abstract: Antimicrobial peptides (AMPs) have been extensively investigated as potential antibiotics because the activity of these small cationic peptides can be enhanced by rational design. Many AMPs appear to bind and subsequently disrupt the integrity of… read more here.
Keywords: gram negative; negative bacteria; rational design; antimicrobial peptides ... See more keywords