Evaluation of Triple-Negative Breast Cancer Early Detection via Mammography Screening and Outcomes in African American and White American Patients.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA surgery"
DOI: 10.1001/jamasurg.2019.6032
Abstract: This cohort study examines triple-negative breast cancer detection via mammography screening, treatment, and survival rates in African American and white American women. read more here.
Keywords: negative breast; breast cancer; detection via; mammography screening ... See more keywords
Hormone Receptor Status of Second Breast Cancers in Women With Triple-Negative Breast Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA surgery"
DOI: 10.1001/jamasurg.2025.0100
Abstract: This cohort study investigates chemoprevention in patients with triple-negative breast cancer experiencing subsequent in-breast events. read more here.
Keywords: breast cancer; breast; hormone receptor; negative breast ... See more keywords
Genomewide binding of transcription factor Snail1 in triple‐negative breast cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12317
Abstract: Transcriptional regulation mediated by the zinc finger protein Snail1 controls early embryogenesis. By binding to the epithelial tumor suppressor CDH1 gene, Snail1 initiates the epithelial–mesenchymal transition (EMT). The EMT generates stem‐like cells and promotes invasiveness… read more here.
Keywords: negative breast; breast; snail1; breast cancer ... See more keywords
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple‐negative breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12856
Abstract: Dependence on glutamine and acceleration of fatty acid oxidation (FAO) are both metabolic characteristics of triple‐negative breast cancer (TNBC). With the rapid growth of tumors, accelerated glutamine catabolism depletes local glutamine, resulting in glutamine deficiency.… read more here.
Keywords: negative breast; hrd1; fatty acid; breast cancer ... See more keywords
Nicotinamide (niacin) supplement increases lipid metabolism and ROS‐induced energy disruption in triple‐negative breast cancer: potential for drug repositioning as an anti‐tumor agent
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13209
Abstract: Metabolic dysregulation is an important hallmark of cancer. Nicotinamide (NAM), a water‐soluble amide form of niacin (vitamin B3), is currently available as a supplement for maintaining general physiologic functions. NAM is a crucial regulator of… read more here.
Keywords: metabolism; supplement; triple negative; ros ... See more keywords
Enhancing therapeutic efficacy in triple‐negative breast cancer and melanoma: synergistic effects of modulated electro‐hyperthermia (mEHT) with NSAIDs especially COX‐2 inhibition in in vivo models
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13585
Abstract: Triple‐negative breast cancer (TNBC) is a leading cause of cancer mortality and lacks modern therapy options. Modulated electro‐hyperthermia (mEHT) is an adjuvant therapy with demonstrated clinical efficacy for the treatment of various cancer types. In… read more here.
Keywords: cancer; breast cancer; meht; negative breast ... See more keywords
Biomimetic Tumor Cell Membrane‐Encapsulated Nanoparticles Combine NIR‐II Photothermal Therapy and Chemotherapy for Enhanced Immunotherapy in Triple‐Negative Breast Cancer
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DOI: 10.1002/adfm.202410841
Abstract: To advance the understanding and potential treatment strategies for triple‐negative breast cancer (TNBC), particularly focusing on its high metastatic propensity and uncertain molecular targets, a biomimetic tumor cell membrane‐encapsulated nanodelivery system is developed for enhanced… read more here.
Keywords: breast cancer; negative breast; tumor; cell ... See more keywords
GSH‐Responsive Mn2+ Burst Nanoboxes as Mitophagy Intervention Agents Augment Ferroptosis and Chemoimmunotherapy in Triple‐Negative Breast Cancer
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DOI: 10.1002/adfm.202500491
Abstract: Chemoimmunotherapy is recognized as a promising approach for treating cancer patients. However, the overall therapeutic efficacy of treatments for triple‐negative breast cancer (TNBC) is compromised by several factors, including its highly immunosuppressive tumor microenvironment, the… read more here.
Keywords: cancer; breast cancer; negative breast; gsh responsive ... See more keywords
Genetically Engineered Bacteria‐Derived Hydrogel Orchestrates T Cell Spatial Dynamics for Triple‐Negative Breast Cancer Immunotherapy
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DOI: 10.1002/adfm.202511779
Abstract: Impaired spatial dynamics of T cells represent a major challenge to effective immunotherapy in triple‐negative breast cancer (TNBC). Here, a genetically engineered, bacteria‐derived hydrogel is presented that precisely orchestrates T cell activation, trafficking, and tumor… read more here.
Keywords: spatial dynamics; immunotherapy; negative breast; cell ... See more keywords
A Honeycomb-Like Bismuth/Manganese Oxide Nanoparticle with Mutual Reinforcement of Internal and External Response for Triple-Negative Breast Cancer Targeted Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100518
Abstract: Triple-negative breast cancer (TNBC) exhibits aggressive behavior and high levels of metastasis owing to its complex heterogeneous structure and lack of specific receptors. Here, tumor cell membrane (CM)-coated bismuth/manganese oxide nanoparticles (NPs) with high indocyanine… read more here.
Keywords: negative breast; response; breast cancer; external response ... See more keywords
Versatile Red Blood Cells for Triple‐Negative Breast Cancer Treatment via Stepwise Photoactivations
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DOI: 10.1002/adhm.202201690
Abstract: Phototherapies have many advantages for triple‐negative breast cancer (TNBC) treatment. However, their effects are often limited by short blood circulation time, poor tumor selectivity and weak penetration of phototherapeutic agents, and tumor hypoxia. For overcoming… read more here.
Keywords: red blood; triple negative; breast cancer; blood ... See more keywords