Less can be more: A finite treatment approach for HBeAg‐negative chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29821
Abstract: Long-term administration of potent nucleos (t)ide analogs (NAs) is the cornerstone of antiviral therapy for hepatitis B e antigen (HBeAg)-negative chronic hepatitis B, as it reduces liver-related complications by efficiently suppressing viral replication. Although there… read more here.
Keywords: hepatitis; hbeag negative; relapse; negative chronic ... See more keywords
HBV pre‐core mutant in genotype‐D infected children is selected during HBeAg/anti‐HBe seroconversion and leads to HBeAg negative chronic hepatitis B in adulthood
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25068
Abstract: Selection of HBeAg defective HBV mutants (mt) during childhood might influence infection outcome in adults. Aim of this study was to correlate the dynamics of pre‐core HBV mutant (pre‐C mt) selection with virological/clinical outcomes in… read more here.
Keywords: hbv; pre; hbeag negative; negative chronic ... See more keywords
Helicobacter pylori-negative Chronic Gastritis in Children: A Systematic Review
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DOI: 10.1097/mpg.0000000000003414
Abstract: ABSTRACT Objectives: To systematically review the current evidence on Helicobacter pylori-negative chronic gastritis including natural history, available therapies and outcomes. Methods: Articles providing data on the prevalence, treatment or outcomes of Helicobacter pylori-negative gastritis were… read more here.
Keywords: chronic gastritis; negative chronic; gastritis; helicobacter pylori ... See more keywords
p38 mitogen‐activated protein kinase impairment of innate immune cells is a characteristic feature of HBeAg‐negative chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13209
Abstract: The mitogen‐activated protein kinase p38 (MAPK) is implicated in the induction of immune responses by regulating the differentiation of T lymphocytes and production of cytokines. Our aim was to investigate p38MAPK phosphorylation in different stages… read more here.
Keywords: hepatitis; hbeag negative; p38; negative chronic ... See more keywords
De novo combination antiviral therapy in e antigen‐negative chronic hepatitis B virus‐infected paediatric patients with advanced fibrosis
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DOI: 10.1111/jvh.13372
Abstract: To date, studies that focus on treatment of e antigen‐negative chronic hepatitis B virus‐infected children with advanced fibrosis are extremely limited. This puts these patients at risk of rapid disease progression. Our study aimed to… read more here.
Keywords: hepatitis; paediatric patients; negative chronic; chronic hepatitis ... See more keywords
Predictive Value of HBsAg for Off-treatment Response in HBeAg-negative Chronic Hepatitis B Patients.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the College of Physicians and Surgeons--Pakistan : JCPSP"
DOI: 10.29271/jcpsp.2023.01.47
Abstract: OBJECTIVE To investigate the virological relapse (VR) rate and prognostic value of the HBsAg level at treatment completion for predicting sustained off-treatment response in HBeAg-negative patients after neucleos(t)ide analog (NA) therapy. STUDY DESIGN Prospective observational… read more here.
Keywords: negative chronic; hbeag negative; treatment; treatment response ... See more keywords
Characteristics of an Outpatient Cohort with HBeAg-Negative Chronic Hepatitis B
Sign Up to like & getrecommendations! Published in 2019 at "Open Access Macedonian Journal of Medical Sciences"
DOI: 10.3889/oamjms.2019.623
Abstract: BACKGROUND: Patients with hepatitis Be antigen-negative chronic hepatitis B (HBeAg-negative CHB), and patients’ inactive carriers (IC) have similar laboratory and serologic characteristics and are not always easy to distinguish. AIM: To characterise hepatitis Be antigen… read more here.
Keywords: hepatitis; serology; hbeag negative; negative chronic ... See more keywords