Assessing the Quality and Making Appropriate Use of Historical Negative Control Data: A Report of the International Workshop on Genotoxicity Testing (IWGT).
Sign Up to like & getrecommendations! Published in 2023 at "Environmental and molecular mutagenesis"
DOI: 10.1002/em.22541
Abstract: Historical negative control data (HCD) have played an increasingly important role in interpreting the results of genotoxicity tests. In particular, Organisation for Economic Co-operation and Development (OECD) genetic toxicology Test Guidelines recommend comparing responses produced… read more here.
Keywords: genotoxicity testing; hcd; genotoxicity; negative control ... See more keywords
Pragmatic considerations for negative control outcome studies to guide non‐randomized comparative analyses: A narrative review
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5623
Abstract: This narrative review describes the application of negative control outcome (NCO) methods to assess potential bias due to unmeasured or mismeasured confounders in non‐randomized comparisons of drug effectiveness and safety. An NCO is assumed to… read more here.
Keywords: narrative review; negative control; non randomized; control outcome ... See more keywords
Negative control of cytokinesis by stress-activated MAPK signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Current genetics"
DOI: 10.1007/s00294-021-01155-6
Abstract: Mitogen-activated protein kinase (MAPK) signalling pathways regulate multiple cellular functions in eukaryotic organisms in response to environmental cues, including the dynamic remodeling of the actin cytoskeleton. The fission yeast S. pombe is an optimal model… read more here.
Keywords: stress activated; cytokinesis; car; negative control ... See more keywords
Two component system CpxR/A regulates the prodigiosin biosynthesis by negative control in Serratia marcescens FS14.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.09.050
Abstract: Prodigiosin is a tripyrrole red secondary metabolite synthesized by many microorganisms, including Serratia marcescens. In this study, we found that the deletion of the gene of sensor kinase CpxA dramatically decreased the prodigiosin production, while… read more here.
Keywords: cpxr; prodigiosin biosynthesis; negative control; regulates prodigiosin ... See more keywords
Children with poor attachment to their parents: Explanatory variables as a function of their perception of their parents' behavior
Sign Up to like & getrecommendations! Published in 2018 at "Children and Youth Services Review"
DOI: 10.1016/j.childyouth.2018.02.034
Abstract: Abstract An investigation was developed to determine the extent to which some children express detachment toward their parents and, in such cases, to determine the parental behaviors that predict this tendency. Participants were 3000 minors… read more here.
Keywords: control; attachment parents; parents explanatory; negative control ... See more keywords
Laterally Aggregated Polyacrylamide Gels for Immunoprobed Isoelectric Focusing.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b04913
Abstract: Immunoprobed isoelectric focusing (IEF) resolves proteins based on differences in isoelectric point (pI) and then identifies protein targets through immunoprobing of IEF-separated proteins that have been immobilized onto a gel scaffold. During the IEF stage,… read more here.
Keywords: isoelectric focusing; negative control; gel; highly porous ... See more keywords
Feed supplementation with some natural products on Salmonella infected broilers’ performance and intestinal injury during the starter period
Sign Up to like & getrecommendations! Published in 2020 at "Italian Journal of Animal Science"
DOI: 10.1080/1828051x.2020.1814170
Abstract: Abstract Many alternatives are under investigation since 2006 when the European Union banned the use of antimicrobials in animal feed. The objective of this study was to find the effect of different feed additives in… read more here.
Keywords: broiler; control; feed; salmonella ... See more keywords
Examining associations between physical activity and cardiovascular mortality using negative control outcomes.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of epidemiology"
DOI: 10.1093/ije/dyy272
Abstract: Background The purpose of a negative control is to reproduce a condition that cannot involve the hypothesized causal mechanism, but does involve the same sources of bias and confounding that may distort the primary association… read more here.
Keywords: cvd; physical activity; negative control; mortality ... See more keywords
Negative Control Exposures: Causal Effect Identifiability and Use in Probabilistic-bias and Bayesian Analyses With Unmeasured Confounders
Sign Up to like & getrecommendations! Published in 2022 at "Epidemiology"
DOI: 10.1097/ede.0000000000001528
Abstract: Background: Probabilistic bias and Bayesian analyses are important tools for bias correction, particularly when required parameters are nonidentifiable. Negative controls are another tool; they can be used to detect and correct for confounding. Our goals… read more here.
Keywords: bayesian analyses; control; probabilistic bias; negative control ... See more keywords
Parental autonomy support in relation to preschool aged children’s behavior: Examining positive guidance, negative control, and responsiveness
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Child Psychology and Psychiatry"
DOI: 10.1177/1359104521999762
Abstract: This study evaluated the relationship between parental autonomy support and preschool-aged children’s display of autonomy. Specifically, we examined if mothers’ and fathers’ use of positive guidance, negative control, and responsiveness during parent-child interactions predicted children’s… read more here.
Keywords: responsiveness; guidance negative; negative control; positive guidance ... See more keywords
Using fathers as a negative control exposure to test the Developmental Origins of Health and Disease Hypothesis: A case study on maternal distress and offspring asthma using Swedish register data
Sign Up to like & getrecommendations! Published in 2017 at "Scandinavian Journal of Public Health"
DOI: 10.1177/1403494817702324
Abstract: Background: Developmental Origins of Health and Disease Hypothesis (DOHaD) studies are often observational in nature and are therefore prone to biases from loss to follow-up and unmeasured confounding. Register-based studies can reduce these issues since… read more here.
Keywords: maternal distress; offspring asthma; negative control; health ... See more keywords