Evolution of negative immune regulators
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007913
Abstract: Hosts must recognize pathogen invasion and respond rapidly. The need for speed requires a low threshold for triggering a response, causing occasional false alarms. Host immune systems therefore require strong negative regulators to shut down… read more here.
Keywords: negative regulators; immune regulators; negative immune; evolution negative ... See more keywords
Immune Evasion, a Potential Mechanism of Trichothecenes: New Insights into Negative Immune Regulations
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19113307
Abstract: Days ago, the Nobel Prize in Physiology or Medicine 2018 was awarded jointly to James P. Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation”. This news has… read more here.
Keywords: evasion potential; mechanism; immune evasion; negative immune ... See more keywords