Jumping into the future: overcoming pharmacokinetic/pharmacodynamic hurdles to optimize the treatment of severe difficult to treat-Gram-negative infections with novel beta-lactams
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2023.2169131
Abstract: ABSTRACT Introduction The choice of best therapeutic strategy for difficult-to-treat resistance (DTR) Gram-negative infections currently represents an unmet clinical need. Areas covered This review provides a critical reappraisal of real-world evidence supporting the role of… read more here.
Keywords: dtr gram; difficult treat; novel beta; negative infections ... See more keywords
2439. Outcomes of Minocycline Use on Gram-Negative Infections and Implications of MIC
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DOI: 10.1093/ofid/ofy210.2092
Abstract: Abstract Background Minocycline (MINO) is a treatment option for Acinetobacter baumannii and Stenotrophomonas maltophilia infections due to high in vitro susceptibility. Literature suggests it may also be an option for carbapenamase-producing enterobacteriaceae. MINO minimum inhibitory… read more here.
Keywords: gram negative; treatment; mino; negative infections ... See more keywords
520. The Clinical Profile and Outcomes of Patients given Intravenous Colistin for Multidrug-Resistant Gram-negative Infections in a Philippine Tertiary Hospital
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DOI: 10.1093/ofid/ofz360.589
Abstract: Abstract Background Colistimethate sodium (colistin) is used to treat multi-drug-resistant Gram-negative infections. We describe the profile and outcomes of patients given colistin in a tertiary level government hospital. Methods We performed a retrospective cross-sectional study… read more here.
Keywords: outcomes patients; gram negative; hospital; negative infections ... See more keywords
An In Vitro Model of the Efficacy of Breast Implant Irrigant Solutions Against Gram-Negative Infections
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DOI: 10.1097/sap.0000000000003302
Abstract: Background In implant-based breast surgery, infections remain a clinically challenging complication. Surgeons often prophylactically address this risk by irrigating the implant at the time of placement. However, there remain few data on the ideal irrigant… read more here.
Keywords: breast implant; irrigant solutions; negative infections; gram negative ... See more keywords
Clinical efficacy of renal dosing adjustments of ceftazidime–avibactam in patients affected by carbapenem‐resistant Gram‐negative infections: A systematic review and meta‐analysis of observational studies
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DOI: 10.1111/bcp.15586
Abstract: The aim of this study is to assess clinical efficacy of ceftazidime–avibactam for the management of carbapenem‐resistant Gram‐negative infections in renal patients receiving recommended dosing adjustments compared to those treated with scheduled full‐dose. read more here.
Keywords: carbapenem resistant; ceftazidime avibactam; clinical efficacy; resistant gram ... See more keywords
Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
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DOI: 10.1155/2017/3635609
Abstract: Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making.… read more here.
Keywords: mdr; gram negative; evidence; negative infections ... See more keywords
Strategies to reduce Gram-negative infections: a community perspective.
Sign Up to like & getrecommendations! Published in 2020 at "British journal of community nursing"
DOI: 10.12968/bjcn.2020.25.5.240
Abstract: Infections caused by Gram-negative bacteria continue to be on the rise, despite efforts by the Government and health service to curb their numbers. Most of these infections arise in the community. The case for targeting… read more here.
Keywords: gram negative; community; reduce gram; negative infections ... See more keywords
Ceftazidime/Avibactam and Ceftolozane/Tazobactam: Novel Therapy for Multidrug Resistant Gram Negative Infections in Children.
Sign Up to like & getrecommendations! Published in 2018 at "Current pediatric reviews"
DOI: 10.2174/1573396314666180308150908
Abstract: The rise in Multidrug-resistant (MDR) infections has become a significant problem in both the developing countries and in the United States (U.S.). Specifically, MDR gram-negative infections are emerging, affecting not only adults but children as… read more here.
Keywords: ceftazidime avibactam; gram negative; ceftolozane tazobactam; negative infections ... See more keywords