Should familial disease be considered as a negative prognostic factor in micropapillary thyroid carcinoma?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-019-01039-0
Abstract: PurposeAn increased aggressiveness of familial papillary thyroid carcinoma (FPTC) compared with sporadic form has been reported. On the contrary, the biological behavior of familial microPTC (FmPTC) is still debated. To assess if familial diseases should… read more here.
Keywords: negative prognostic; prognostic factor; disease; familial disease ... See more keywords
The impact of MET, IGF-1, IGF1R expression and EGFR mutations on survival of patients with non-small-cell lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0181527
Abstract: Introduction To compare the efficacy of silver in situ hybridization (SISH) and immunohistochemistry (IHC) in detecting MET and IGF1R alterations and to investigate their prevalence and prognostic significance. A possible correlation between MET receptor expression,… read more here.
Keywords: negative prognostic; met igf; gene copy; expression ... See more keywords
EZH2 is a negative prognostic biomarker associated with immunosuppression in hepatocellular carcinoma
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DOI: 10.1371/journal.pone.0242191
Abstract: The enhancer of zeste homolog 2 (EZH2) plays a critical role in different components of anti-tumor immunity. However, the specific role of EZH2 in modulating MHC Class I antigen presentation and T cell infiltration have… read more here.
Keywords: negative prognostic; ezh2; ezh2 negative; expression ... See more keywords
FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma
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DOI: 10.18632/oncotarget.16848
Abstract: Background FBXW7 functions as a ubiquitin ligase tagging multiple dominant oncogenic proteins and commonly mutates in colorectal cancer. Data suggest missense mutations lead to greater loss of FBXW7 function than other gene aberrations do. However,… read more here.
Keywords: metastatic colorectal; fbxw7 missense; missense mutations; negative prognostic ... See more keywords