LcrQ Coordinates with the YopD-LcrH Complex To Repress lcrF Expression and Control Type III Secretion by Yersinia pseudotuberculosis
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DOI: 10.1128/mbio.01457-21
Abstract: All three human-pathogenic Yesinia species, Y. pestis, Y. enterocolitica, and Y. pseudotuberculosis, employ a plasmid-encoded T3SS to target immunomodulatory effectors into host immune cells. Several plasmid-encoded regulators influence T3SS control, including the master transcriptional activator… read more here.
Keywords: lcrh; yopd lcrh; negative regulatory; lcrq ... See more keywords
Identification of potential crucial genes and construction of microRNA-mRNA negative regulatory networks in osteosarcoma
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DOI: 10.1186/s41065-018-0061-9
Abstract: BackgroundThis study aimed to identify potential crucial genes and construction of microRNA-mRNA negative regulatory networks in osteosarcoma by comprehensive bioinformatics analysis.MethodsData of gene expression profiles (GSE28424) and miRNA expression profiles (GSE28423) were downloaded from GEO… read more here.
Keywords: network; mrna negative; microrna mrna; negative regulatory ... See more keywords
Double Negative T Regulatory Cells: An Emerging Paradigm Shift in Reproductive Immune Tolerance?
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DOI: 10.3389/fimmu.2022.886645
Abstract: Immune regulation of female reproductive function plays a crucial role in fertility, as alterations in the relationship between immune and reproductive processes result in autoimmune subfertility or infertility. The breakdown of immune tolerance leads to… read more here.
Keywords: negative regulatory; double negative; immune tolerance; regulatory cells ... See more keywords