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Published in 2025 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.5c02298
Abstract: Drug repositioning accelerates therapeutic discovery, but existing computational methods are hampered by representation collapse, noisy supervision, and suboptimal negative sampling. To address these limitations, we introduce MGTAL-DR, a novel graph learning framework that integrates a…
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Keywords:
drug repositioning;
drug;
adversarial contrastive;
dual channel ... See more keywords
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Published in 2022 at "IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing"
DOI: 10.1109/jstars.2022.3220514
Abstract: Hyperspectral anomaly detection (HAD) aims at detecting the anomalies without any prerequisite information, which gains lots of attention in recent years. Most of existing detectors locate the anomalies by eliminating the background. The background is…
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Keywords:
negative sampling;
hyperspectral anomaly;
dynamic negative;
anomaly detection ... See more keywords
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Published in 2025 at "IEEE Transactions on Computational Social Systems"
DOI: 10.1109/tcss.2025.3571909
Abstract: Multimodal recommendation has become a key technology for social media platforms. It is widely used in content recommendation, user preference analysis, advertisement placement, etc. Existing recommendation methods mainly focus on learning multimodal embeddings from direct…
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Keywords:
users items;
multimodal recommendation;
indirect interactions;
true negative ... See more keywords
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Published in 2023 at "IEEE Transactions on Knowledge and Data Engineering"
DOI: 10.1109/tkde.2022.3155155
Abstract: Graph-based recommendation systems are blossoming recently, which models user-item interactions as a user-item graph and utilizes graph neural networks (GNNs) to learn the embeddings for users and items. A fundamental challenge of graph-based recommendation is…
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Keywords:
negative sampling;
mml mml;
mml;
tex math ... See more keywords
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Published in 2022 at "IEEE Transactions on Pattern Analysis and Machine Intelligence"
DOI: 10.1109/tpami.2022.3141095
Abstract: The recently proposed Collaborative Metric Learning (CML) paradigm has aroused wide interest in the area of recommendation systems (RS) owing to its simplicity and effectiveness. Typically, the existing literature of CML depends largely on the…
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Keywords:
negative sampling;
metric learning;
without negative;
efficient alternative ... See more keywords
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Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-3269-4
Abstract: Imbalanced datasets are commonly encountered in bioinformatics classification problems, that is, the number of negative samples is much larger than that of positive samples. Particularly, the data imbalance phenomena will make us underestimate the performance…
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Keywords:
positive samples;
pseudo negative;
negative sampling;
negative samples ... See more keywords