Nanopharmaceuticals as a solution to neglected diseases: Is it possible?
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.02.019
Abstract: The study of neglected diseases has not received much attention, especially from public and private institutions over the last years, in terms of strong support for developing treatment for these diseases. Support in the form… read more here.
Keywords: treatment; nanopharmaceuticals solution; diseases possible; solution neglected ... See more keywords
Histone deacetylase enzymes as potential drug targets of Neglected Tropical Diseases caused by cestodes
Sign Up to like & getrecommendations! Published in 2019 at "International Journal for Parasitology: Drugs and Drug Resistance"
DOI: 10.1016/j.ijpddr.2019.02.003
Abstract: Cestode parasites cause neglected diseases, such as echinococcosis and cysticercosis, which represent a significant problem in human and animal health. Benzimidazoles and praziquantel are the only available drugs for chemotherapy and it is therefore important… read more here.
Keywords: drug targets; caused cestodes; diseases caused; drug ... See more keywords
Turning up the heat on neglected diseases
Sign Up to like & getrecommendations! Published in 2019 at "Nature Medicine"
DOI: 10.1038/s41591-019-0514-3
Abstract: Climate change makes the challenge of certain tropical ailments even tougher. read more here.
Keywords: heat neglected; neglected diseases; turning heat; medicine ... See more keywords
Optical Coherence Tomography and Optical Coherence Tomography Angiography in Neglected Diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2023.2211161
Abstract: A group of self-limiting and frequently neglected diseases exist in the literature like Rickettsial disease, Malaria, Dengue fever, Chikungunya, West Nile virus infection, Rift Valley fever, Bartonellosis, or Lyme disease which are poorly understood due… read more here.
Keywords: coherence tomography; neglected diseases; optical coherence; angiography ... See more keywords
Potential triazole-based molecules for the treatment of neglected diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666170727103901
Abstract: Neglected Diseases (NDs) affect million of people, especially the poorest population around the world. Several efforts to an effective treatment have proved insufficient at the moment. In this context, triazole derivatives have shown great relevance… read more here.
Keywords: triazole; based molecules; treatment; chemistry ... See more keywords
Neglected Diseases - New Compounds and Treatments.
Sign Up to like & getrecommendations! Published in 2019 at "Current medicinal chemistry"
DOI: 10.2174/092986732624190927115600
Abstract: read more here.
Keywords: compounds treatments; chemistry; diseases new; neglected diseases ... See more keywords
Recent Neglected Drug Design Studies.
Sign Up to like & getrecommendations! Published in 2021 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026621666210920155939
Abstract: BACKGROUND Neglected diseases require special attention when looking for new therapeutic alternatives, as these are diseases of extreme complexity and severity that affect populations belonging to lower social classes who are lacking access to basic… read more here.
Keywords: medicinal chemistry; chemistry; drug design; neglected drug ... See more keywords
Retrospective Review of Chromane Analogues as Anti-Protozoal Leads: A Decade's Worth of Evolution.
Sign Up to like & getrecommendations! Published in 2023 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026623666230214093147
Abstract: Tropical, vector-borne, and neglected diseases with a limited number of medication therapies include Leishmaniasis, Malaria, Chagas and Human African Trypanosomiasis (HAT). Chromones are a large class of heterocyclic compounds with significant applications. This heterocycle has… read more here.
Keywords: review chromane; neglected diseases; review; chromane ... See more keywords
Employing "Red Flags" to Fight the Most Neglected Diseases: Nitroaromatic as Still Suitable Tools to Treat Human and Veterinary Parasitosis.
Sign Up to like & getrecommendations! Published in 2023 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026623666230427114840
Abstract: Nitroaromatic compounds have been used for treating parasitic diseases since the 1960s. Pharmacological alternatives to treat them are under observation. However, for the most neglected diseases, such as those caused by worms and less known… read more here.
Keywords: parasitosis; neglected diseases; employing red; nitro compounds ... See more keywords
Drug Repositioning: Concept, Classification, Methodology, and Importance in Rare/Orphans and Neglected Diseases -
Sign Up to like & getrecommendations! Published in 2018 at "journal of applied pharmaceutical science"
DOI: 10.7324/japs.2018.8822
Abstract: The development of new drugs is a long and complex process, with extremely high investment and small expectation of success. In recent years, there was a significant decline in the number of new drugs approved… read more here.
Keywords: methodology; drug repositioning; drug; orphans neglected ... See more keywords