Structure‐based design of ferritin nanoparticle immunogens displaying antigenic loops of Neisseria gonorrhoeae
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12267
Abstract: Effective vaccines are urgently needed to combat gonorrhea, a common sexually transmitted bacterial infection, for which treatment options are diminishing due to rapid emergence of antibiotic resistance. We have used a rational approach to the… read more here.
Keywords: neisseria gonorrhoeae; ferritin nanoparticle; antigenic peptides; structure ... See more keywords
Antimicrobial‐resistant Neisseria gonorrhoeae can be targeted using inhibitors against evolutionary conservedl‐asparaginase
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30271
Abstract: The emergence of multiple drug‐resistant “super gonorrhoea” complicates the management and treatment of Neisseria gonorrhoeae infections due to the progressive accumulation of mutations in the biological targets of frontline antimicrobials. Continuous evaluation and reporting of… read more here.
Keywords: neisseria gonorrhoeae; asparaginase; antimicrobial resistant; drug ... See more keywords
Prevalence of Ureaplasma urealyticum, Chlamydia trachomatis, and Neisseria gonorrhoeae in gynecological outpatients, Taizhou, China
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23072
Abstract: Ureaplasma urealyticum (UU), Chlamydia trachomatis (CT), and Neisseria gonorrhoeae (NG) are highly prevalent worldwide and may lead to some genital diseases. The objective of this large‐scale study was to estimate the prevalence characteristics of UU,… read more here.
Keywords: ureaplasma urealyticum; urealyticum chlamydia; chlamydia trachomatis; neisseria gonorrhoeae ... See more keywords
Antimicrobial Blue Light Inactivation of Neisseria gonorrhoeae: Roles of Wavelength, Endogenous Photosensitizer, Oxygen, and Reactive Oxygen Species
Sign Up to like & getrecommendations! Published in 2019 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23104
Abstract: The aim of this study was to investigate the efficacy, safety, and mechanism of action of antimicrobial blue light (aBL) for the inactivation of Neisseria gonorrhoeae, the etiological agent of gonorrhea. read more here.
Keywords: blue light; oxygen; antimicrobial blue; neisseria gonorrhoeae ... See more keywords
Structures of glyceraldehyde 3‐phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis
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DOI: 10.1002/pro.3824
Abstract: Neisseria gonorrhoeae (Ng) and Chlamydia trachomatis (Ct) are the most commonly reported sexually transmitted bacteria worldwide and usually present as co‐infections. Increasing resistance of Ng to currently recommended dual therapy of azithromycin and ceftriaxone presents… read more here.
Keywords: glyceraldehyde phosphate; phosphate dehydrogenase; neisseria gonorrhoeae; gonorrhoeae chlamydia ... See more keywords
Transformation in Neisseria gonorrhoeae.
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DOI: 10.1007/978-1-4939-9496-0_10
Abstract: Laboratory techniques for transformation of the pathogenic Neisseria are well developed, and take advantage of the natural transformability of these species. More recently, these techniques have been successfully applied to some nonpathogenic species of Neisseria… read more here.
Keywords: neisseria gonorrhoeae; biology; transformation neisseria; transformation ... See more keywords
Strategies for Global RNA Sequencing of the Human Pathogen Neisseria gonorrhoeae.
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DOI: 10.1007/978-1-4939-9496-0_11
Abstract: Over the last several years transcriptomic analysis of bacterial pathogens has become easier and less expensive. This technique is used to determine expression levels for all genes of a particular species or collection of species… read more here.
Keywords: analysis; rna; pathogen neisseria; neisseria gonorrhoeae ... See more keywords
Phenotypic MicroArray Screening of Neisseria gonorrhoeae in Chemically Defined Liquid Medium.
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DOI: 10.1007/978-1-4939-9496-0_13
Abstract: Phenotype MicroArrays (PMs) provide a considerable benefit to the evaluation of potential vaccine/drug targets and the assessment of hypothetical protein function. Nearly 2000 conditions can be screened relatively quickly either to search for phenotypes associated… read more here.
Keywords: phenotypic microarray; liquid medium; phenotypic; neisseria gonorrhoeae ... See more keywords
Use of Human Monocyte-Derived Macrophages to Study Neisseria gonorrhoeae Infection.
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DOI: 10.1007/978-1-4939-9496-0_18
Abstract: Macrophages are critical cells in the innate immune response to microorganisms sensed in the tissues. During infections, the interaction between pathogens and macrophages leads to a macrophage response that includes cytokine production, antigen processing and… read more here.
Keywords: response; infection; human monocyte; neisseria gonorrhoeae ... See more keywords
How to Identify Exposed Women Who Are Infected with Neisseria gonorrhoeae.
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DOI: 10.1007/978-1-4939-9496-0_2
Abstract: Treatment trials of antibiotics for Neisseria gonorrhoeae infections frequently enroll primarily men with urethritis, as the diagnosis of acute gonococcal infection in men with urethritis is easily made by Gram stain of the urethral exudate,… read more here.
Keywords: treatment; women infected; neisseria gonorrhoeae; identify exposed ... See more keywords
In Vitro Models of Eye Infection with Neisseria gonorrhoeae.
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DOI: 10.1007/978-1-4939-9496-0_21
Abstract: Prophylaxis with silver nitrate and later antibiotics has significantly reduced the cases of infant blindness from gonococcal infection at birth to the point where it has all but been forgotten in the developed world as… read more here.
Keywords: infection; neisseria gonorrhoeae; models eye; eye infection ... See more keywords