Regulation of Neisseria meningitidis cytochrome bc 1 components by NrrF, a Fur‐controlled small noncoding RNA
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DOI: 10.1002/2211-5463.12266
Abstract: NrrF is a small regulatory RNA of the human pathogen Neisseria meningitidis. NrrF was previously shown to repress succinate dehydrogenase (sdhCDAB) under control of the ferric uptake regulator (Fur). Here, we provide evidence that cytochrome… read more here.
Keywords: cytochrome components; rna; cytochrome bc1; meningitidis cytochrome ... See more keywords
In Vitro Models for Studying the Interaction of Neisseria meningitidis with Human Brain Endothelial Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9202-7_10
Abstract: Bacterial meningitis is a serious, life-threatening infection of the central nervous system (CNS). To cause meningitis, bacteria must interact with and penetrate the meningeal blood-cerebrospinal fluid barrier (mB/CSFB), which comprises highly specialized brain endothelial cells.… read more here.
Keywords: brain endothelial; endothelial cells; interaction; neisseria meningitidis ... See more keywords
HN, N, Cα and Cβ assignments of the two periplasmic domains of Neisseria meningitidis DsbD
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DOI: 10.1007/s12104-017-9743-x
Abstract: DsbD is a disulfide bond reductase present in the inner membrane of many Gamma-Proteobacteria. In the human pathogen Neisseria meningitidis, DsbD is required for viability and represents a potential target for the development of antibiotics.… read more here.
Keywords: domains neisseria; two periplasmic; meningitidis dsbd; assignments two ... See more keywords
The first pediatric case of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) associated with Neisseria meningitidis
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Development"
DOI: 10.1016/j.braindev.2021.09.002
Abstract: BACKGROUND Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinic-radiological syndrome characterized by neurological deficiencies and reversible magnetic resonance imaging findings in the splenium of the corpus callosum. Usually, it has a good… read more here.
Keywords: encephalopathy reversible; reversible splenial; encephalitis encephalopathy; mild encephalitis ... See more keywords
Intermittent Pili-Mediated Forces Fluidize Neisseria meningitidis Aggregates Promoting Vascular Colonization
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DOI: 10.1016/j.cell.2018.04.010
Abstract: Neisseria meningitidis, a bacterium responsible for meningitis and septicemia, proliferates and eventually fills the lumen of blood capillaries with multicellular aggregates. The impact of this aggregation process and its specific properties are unknown. We first… read more here.
Keywords: intermittent; intermittent pili; colonization; mediated forces ... See more keywords
Pericarditis due to Neisseria meningitidis serogroup W135
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DOI: 10.1016/j.idcr.2018.02.009
Abstract: Neisseria meningitidis is a well-recognized cause of bacterial meningitis. Although less common, N. meningitidis can also involve extra-meningeal sites, including the pericardium. The frequency of such extra-meningeal clinical manifestations differs depending on N. meningitidis serogroup.… read more here.
Keywords: serogroup w135; pericarditis due; pericarditis; meningitidis serogroup ... See more keywords
Intraventricular empyema caused by Neisseria meningitidis
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DOI: 10.1016/j.idcr.2019.e00503
Abstract: Meningitis is defined as an inflammation of the protective covering of brain and spinal cord collectively called as meninges. Meningeal infection can be complicated by intraventricular empyema. There are 9 cases of intraventricular empyema described… read more here.
Keywords: meningitis; empyema caused; neisseria meningitidis; empyema ... See more keywords
Neisseria meningitidis and cytomegalovirus simultaneous detection in the filmarray meningitis/encephalitis panel and its clinical relevance
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DOI: 10.1016/j.idcr.2019.e00516
Abstract: A BioFire FilmArray Meningitis/Encephalitis test was performed on a 7-month old child suspected for bacterial meningitis. Two pathogens were detected, Neisseria meningitidis and cytomegalovirus (CMV). We verified the filmarray meningitis/encephalitis test by pan-bacterial assay to… read more here.
Keywords: meningitis; meningitis encephalitis; filmarray meningitis; test ... See more keywords
Immunization with recombinant truncated Neisseria meningitidis-Macrophage Infectivity Potentiator (rT-Nm-MIP) protein induces murine antibodies that are cross-reactive and bactericidal for Neisseria gonorrhoeae
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DOI: 10.1016/j.vaccine.2018.05.069
Abstract: Highlights • Antigenicity of rT-N. meningitidis-MIP vaccine batches is reproducible in mice.• Antibodies to rT-Nm-MIP cross-react with surface Ng-MIP and adhere to gonococci.• Antisera to rT-Nm-MIP are cross-bactericidal for gonococci.• Meningococcal OM can be engineered… read more here.
Keywords: recombinant truncated; bactericidal; truncated neisseria; neisseria meningitidis ... See more keywords
Development and pre-clinical evaluation of a synthetic oligosaccharide-protein conjugate vaccine against Neisseria meningitidis serogroup C.
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DOI: 10.1016/j.vaccine.2019.07.053
Abstract: Significant improvement has been made in the development of vaccines against Neisseria meningitidis infections since the introduction of polysaccharide-protein conjugate vaccines. Conventional bacterial capsular polysaccharide (PS) based conjugate vaccines require unique and expensive manufacturing facilities,… read more here.
Keywords: conjugate; synthetic oligosaccharide; conjugate vaccine; protein conjugate ... See more keywords
Prevalence and persistence of Neisseria meningitidis carriage in Swedish university students
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DOI: 10.1017/s0950268823000018
Abstract: Abstract The bacterium Neisseria meningitidis causes life-threatening disease worldwide, typically with a clinical presentation of sepsis or meningitis, but can be carried asymptomatically as part of the normal human oropharyngeal microbiota. The aim of this… read more here.
Keywords: university; neisseria meningitidis; meningitidis carriage; prevalence ... See more keywords