Characterization of a small-molecule inhibitor targeting NEMO/IKKβ to suppress colorectal cancer growth
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DOI: 10.1038/s41392-022-00888-1
Abstract: NEMO/IKKβ complex is a central regulator of NF-κB signaling pathway, its dissociation has been considered to be an attractive therapeutic target. Herein, using a combined strategy of molecular pharmacological phenotyping, proteomics and bioinformatics analysis, Shikonin… read more here.
Keywords: small molecule; nemo ikk; inhibitor; ikk ... See more keywords