Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17100-z
Abstract: Diamond Blackfan Anemia (DBA) is a congenital bone marrow failure syndrome associated with ribosomal gene mutations that lead to ribosomal insufficiency. DBA is characterized by anemia, congenital anomalies, and cancer predisposition. Treatment for DBA is… read more here.
Keywords: like kinase; nemo like; blackfan anemia; diamond blackfan ... See more keywords
Nemo-like Kinase Reduces Mutant Huntingtin Levels and Mitigates Huntington's Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Human molecular genetics"
DOI: 10.1093/hmg/ddaa061
Abstract: Nemo-like kinase (NLK), an evolutionarily conserved serine/threonine kinase, is highly expressed in the brain, but its function in the adult brain remains not well understood. In this study, we identify NLK as an interactor of… read more here.
Keywords: like kinase; kinase; mhtt; reduces mutant ... See more keywords
Expression of Nemo-like kinase in cervical squamous cell carcinoma: a clinicopathological study
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DOI: 10.2147/ott.s154188
Abstract: Objective Nemo-like kinase (NLK) has been reported to play different roles in tumors. However, the role of NLK in cervical squamous cell carcinoma (CSCC) remains unknown. In this study, we explored the clinical significance including… read more here.
Keywords: cervical squamous; like kinase; cell carcinoma; squamous cell ... See more keywords