(Neo)adjuvant approaches in lung cancer—paving the road to a cure
Sign Up to like & getrecommendations! Published in 2024 at "memo - Magazine of European Medical Oncology"
DOI: 10.1007/s12254-023-00949-3
Abstract: Immune checkpoint inhibitors (ICI) have revolutionized the treatment landscape of metastatic non-small-cell lung cancer (NSCLC). During the past few years the focus of research has shifted toward examining these therapies in patients with early-stage NSCLC… read more here.
Keywords: lung cancer; early stage; neo adjuvant;
The impact of regular enteral feeding via jejunostomy during neo-adjuvant chemotherapy on body composition in patients with oesophageal cancer
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Nutrition"
DOI: 10.1016/j.clnu.2018.06.1338
Abstract: BACKGROUND Malnourishment and sarcopenia are well documented phenomena in oesophageal cancer. Patients undergoing neo-adjuvant chemotherapy prior to oesophagectomy have complex nutritional needs. AIM To examine the effect of regular nutritional support via feeding jejunostomy on… read more here.
Keywords: chemotherapy; adjuvant chemotherapy; body composition; jejunostomy ... See more keywords
OP53 Health Technology Assessment Acceptability Of Innovative Survival Metrics In Oncology
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s026646231900117x
Abstract: Introduction Most new oncology therapies are studied in the advanced/metastatic setting. However, there is an increasing focus on earlier stage disease. Nevertheless, measuring Overall Survival (OS) in neo-/adjuvant therapy trials can be very challenging due… read more here.
Keywords: technology assessment; survival metrics; neo adjuvant; health ... See more keywords
Neo-adjuvant pembrolizumab in stage IV high-grade serous ovarian cancer: the phase II Neo-Pembro trial
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-58440-y
Abstract: While immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, their efficacy in high-grade serous ovarian cancer (HGSOC) remains limited. Some patients, however, achieve lasting responses, emphasizing the need to understand how tumor microenvironment and molecular… read more here.
Keywords: cancer; high grade; grade serous; ovarian cancer ... See more keywords
A phase II study on the neo-adjuvant combination of pazopanib and radiotherapy in patients with high-risk, localized soft tissue sarcoma
Sign Up to like & getrecommendations! Published in 2021 at "Acta Oncologica"
DOI: 10.1080/0284186x.2021.1971294
Abstract: Abstract Purpose A prior phase I study showed that the neo-adjuvant combination of pazopanib and radiotherapy was well tolerated, and induced promising pathological responses in soft-tissue sarcoma patients. Results of the subsequent prospective, multicenter phase… read more here.
Keywords: tissue sarcoma; combination; pazopanib; neo adjuvant ... See more keywords
Oncological and obstetrical outcomes after neo-adjuvant chemotherapy followed by fertility-sparing surgery in patients with cervical cancer ≥2 cm
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2020-002076
Abstract: Objective There is significant debate between up-front radical trachelectomy versus neo-adjuvant chemotherapy before fertility-sparing surgery in patients with tumors ≥2 cm. The aim of this study was to report on the oncological and obstetrical outcome of… read more here.
Keywords: chemotherapy; surgery; adjuvant chemotherapy; fertility sparing ... See more keywords
Fertility-sparing surgery after neo-adjuvant chemotherapy in women with cervical cancer larger than 4 cm: a systematic review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-003297
Abstract: Objective The objective of this systematic review was to assess the oncologic and fertility outcomes of patients with cervix-confined cancer >4 cm who underwent neo-adjuvant chemotherapy followed by fertility-sparing surgery. Methods This study was registered… read more here.
Keywords: neo adjuvant; surgery; fertility sparing; fertility ... See more keywords
Abstract 1678: Overcoming treatment resistance in advanced bladder cancers using a neo-adjuvant combination with a natural product analog
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1678
Abstract: Urinary bladder cancer (BC) is a common cancer worldwide, with approximately 573,278 new cases and 212,536 deaths arising annually. Tumors detected beyond the transitional zone of the bladder (advanced BC) account for most deaths. In… read more here.
Keywords: bladder; gem; neo adjuvant; resistance ... See more keywords
Decision-Making at Swissmedic, the Swiss Regulatory Agency, with a Focus on (Neo)adjuvant Cancer Treatments
Sign Up to like & getrecommendations! Published in 2024 at "Oncology"
DOI: 10.1159/000536541
Abstract: Abstract Introduction: Additional considerations are required for the benefit-risk assessment of new drugs or indications in the setting of (neo)adjuvant cancer treatment as compared to the metastatic/advanced setting, possibly leading to different decision patterns for… read more here.
Keywords: oncology; decision; agency; adjuvant cancer ... See more keywords
The impact of lung surgery, with or without (neo-)adjuvant therapy, on physical functioning in patients with nonsmall cell lung cancer: a scoping review
Sign Up to like & getrecommendations! Published in 2025 at "European Respiratory Review"
DOI: 10.1183/16000617.0156-2024
Abstract: Background Patients with early stage (I–IIIA) nonsmall cell lung cancer (NSCLC) are typically treated via surgery, often accompanied by (neo-)adjuvant therapy. These interventions impose a significant burden on patients and potentially impact their physical functioning… read more here.
Keywords: surgery; lung; adjuvant therapy; lung surgery ... See more keywords
CRITICS-II: a multicentre randomised phase II trial of neo-adjuvant chemotherapy followed by surgery versus neo-adjuvant chemotherapy and subsequent chemoradiotherapy followed by surgery versus neo-adjuvant chemoradiotherapy followed by surgery in resectable gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4770-2
Abstract: BackgroundAlthough radical surgery remains the cornerstone of cure in resectable gastric cancer, survival remains poor. Current evidence-based (neo)adjuvant strategies have shown to improve outcome, including perioperative chemotherapy, postoperative chemoradiotherapy and postoperative chemotherapy. However, these regimens… read more here.
Keywords: chemotherapy; resectable gastric; chemoradiotherapy; neo adjuvant ... See more keywords