Two Marine Cyanobacterial Aplysiatoxin Polyketides, Neo-debromoaplysiatoxin A and B, with K+ Channel Inhibition Activity.
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DOI: 10.1021/acs.orglett.7b03672
Abstract: The isolation and structure elucidation of two cyanobacterial debromoaplysiatoxin (DAT) analogues, neo-debromoaplysiatoxin A (1) and neo-debromoaplysiatoxin B (2), were reported and found to possess 6/10/6 and 6/6/6 fused-ring systems, respectively, which are rarely seen among… read more here.
Keywords: two marine; marine cyanobacterial; neo debromoaplysiatoxin; cyanobacterial aplysiatoxin ... See more keywords
Structure Elucidation of Two Intriguing Neo-Debromoaplysiatoxin Derivatives from Marine Cyanobacterium Lyngbya sp. Showing Strong Inhibition of Kv1.5 Potassium Channel and Differential Cytotoxicity
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DOI: 10.3390/molecules28062786
Abstract: Two aplysiatoxin derivatives, neo-debromoaplysiatoxin I (1) and neo-debromoaplysiatoxin J (2), were isolated from marine cyanobacterium Lyngbya sp. collected from the South China Sea. Their structures including absolute configurations were assigned by spectroscopic analysis, in combination… read more here.
Keywords: debromoaplysiatoxin; marine cyanobacterium; cyanobacterium lyngbya; neo debromoaplysiatoxin ... See more keywords