Cost-Effectiveness of Neoadjuvant-Adjuvant Treatment Strategies for Women With ERBB2 (HER2)–Positive Breast Cancer
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.27074
Abstract: This economic evaluation modeled the cost-effectiveness of 5 neoadjuvant-adjuvant treatment strategies for women with ERBB2-positive breast cancer. read more here.
Keywords: effectiveness neoadjuvant; neoadjuvant adjuvant; adjuvant treatment; treatment strategies ... See more keywords
Duodenal adenocarcinoma: neoadjuvant and adjuvant therapy strategies
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Orphan Drugs"
DOI: 10.1080/21678707.2019.1684257
Abstract: ABSTRACT Introduction: Duodenal adenocarcinoma (DA) is a relatively rare gastrointestinal malignancy associated with poor outcomes. The mainstay of treatment is surgical resection with regional lymphadenectomy but recurrence rates remain high. Due to the relatively low… read more here.
Keywords: neoadjuvant adjuvant; adenocarcinoma neoadjuvant; therapy; adjuvant therapy ... See more keywords
Feasibility of neoadjuvant and adjuvant intraperitoneal chemotherapy in patients with advanced epithelial ovarian cancer
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DOI: 10.1097/md.0000000000022100
Abstract: Abstract Intraperitoneal (IP) chemotherapy is believed to prolong the survival of patients with advanced ovarian cancer after primary debulking surgery. However, there is little knowledge about IP chemotherapy in the setting of neoadjuvant chemotherapy, and… read more here.
Keywords: chemotherapy; patients advanced; feasibility neoadjuvant; ovarian cancer ... See more keywords
Evaluation of dexrazoxane effect on preventing acute cardiac arrhythmia in patients with breast cancer treated with neoadjuvant/adjuvant anthracycline‐based chemotherapy
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Clinical Practice"
DOI: 10.1111/ijcp.14705
Abstract: Adding dexrazoxane to the treatment during neoadjuvant/adjuvant anthracycline‐based chemotherapy in patients with breast cancer prevents the development of heart failure. In this study, we investigated whether dexrazoxane has a protective effect on arrhythmia resulting from… read more here.
Keywords: patients breast; neoadjuvant adjuvant; adjuvant anthracycline; based chemotherapy ... See more keywords
812 Urelumab (anti-CD137 agonist) in combination with vaccine and nivolumab treatments is safe and associated with pathologic response as neoadjuvant and adjuvant therapy for resectable pancreatic cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-sitc2020.0812
Abstract: Background Data analysis of specimens from prior clinical trials identified the immune co-simulatory molecule CD137 within the tumor microenvironment(TME) of pancreatic ductal adenocarcinoma(PDAC) that remain to be activated following vaccine induced T cell and PD-1… read more here.
Keywords: cd137 agonist; trial; anti cd137; neoadjuvant adjuvant ... See more keywords
Abstract CT285: KEYNOTE-689: A phase 3 study of neoadjuvant and adjuvant pembrolizumab plus standard of care (SOC) in locally advanced (LA) head and neck squamous cell carcinoma (HNSCC)
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DOI: 10.1158/1538-7445.am2020-ct285
Abstract: Background: In phase 2 studies (NCT02296684 and NCT02641093), neoadjuvant and adjuvant pembrolizumab demonstrated a pathological response (PR) and acceptable safety in patients with high-risk, resectable, LA HNSCC. KEYNOTE-689 (NCT03765918) is a randomized, open-label, phase 3… read more here.
Keywords: keynote 689; phase; neoadjuvant adjuvant; hnscc ... See more keywords
A phase II study of atezolizumab as neoadjuvant and adjuvant therapy in patients (pts) with resectable non-small cell lung cancer (NSCLC).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.tps8580
Abstract: TPS8580Background: Trials of neoadjuvant and adjuvant chemotherapy have demonstrated an absolute survival benefit of 5% for patients with early stage disease. Atezolizumab is a humanized IgG1 monoclonal antibody that inhibits PD-L1 from binding to its… read more here.
Keywords: phase; neoadjuvant adjuvant; study; atezolizumab neoadjuvant ... See more keywords
A phase Ib trial of neoadjuvant/adjuvant durvalumab +/- tremelimumab in locally advanced renal cell carcinoma (RCC).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.5021
Abstract: 5021Background: Effective neoadjuvant and adjuvant therapies are lacking in locally advanced RCC. Given robust activity of checkpoint inhibitors in mRCC, a phase Ib trial of perioperative Durvaluma... read more here.
Keywords: neoadjuvant adjuvant; rcc; locally advanced; trial neoadjuvant ... See more keywords
Case report: Multimodal neoadjuvant and adjuvant chemotherapy for hepatic undifferentiated embryonal sarcoma in a young adult
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1004108
Abstract: Hepatic undifferentiated embryonal sarcoma of the liver (UESL) is a rare hepatic malignancy found more commonly in pediatric patients. It has been associated with poor outcomes in adults and the role and timing of systemic… read more here.
Keywords: hepatic undifferentiated; adjuvant chemotherapy; neoadjuvant adjuvant; undifferentiated embryonal ... See more keywords
Current Standards in the Management of Early and Locally Advanced Cervical Cancer: Update on the Benefit of Neoadjuvant/Adjuvant Strategies
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DOI: 10.3390/cancers14102449
Abstract: Simple Summary Cervical cancers is a human papillomavirus infection-induced gynecologic cancer. Due to the uneven access to prevention measures in the world, it is still a leading cause of cancer death in women in low-… read more here.
Keywords: locally advanced; advanced cervical; cervical cancers; neoadjuvant adjuvant ... See more keywords
Neoadjuvant and Adjuvant Systemic Therapy for Newly Diagnosed Stage II–IV Epithelial Ovary, Fallopian Tube, or Primary Peritoneal Carcinoma: A Practice Guideline
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DOI: 10.3390/curroncol29010022
Abstract: Background: This study aims to provide guidance for the use of neoadjuvant and adjuvant systemic therapy in women with newly diagnosed stage II–IV epithelial ovary, fallopian tube, or primary peritoneal carcinoma. Methods: EMBASE, MEDLINE, and… read more here.
Keywords: systemic therapy; therapy; stage; neoadjuvant adjuvant ... See more keywords