DNA methylation biomarkers accurately detect esophageal cancer prior and post neoadjuvant chemoradiation
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5623
Abstract: Esophageal cancer (ECa) is associated with high mortality, mostly due to late diagnosis, precluding curativeintent surgery. Hence, neoadjuvant chemoradiation (ChRT) is recommended in most patients regardless of histological subtype. A proportion of these patients, however,… read more here.
Keywords: methylation; esophageal cancer; neoadjuvant chemoradiation; post ... See more keywords
Prognostic significance of the distribution of lymph node metastasis in rectal cancer after neoadjuvant chemoradiation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.24871
Abstract: This study aimed to evaluate the prognostic significance of lymph node distribution (LND) in rectal cancer after neoadjuvant chemoradiation. read more here.
Keywords: prognostic significance; rectal cancer; neoadjuvant chemoradiation; lymph node ... See more keywords
Factors associated with pathologic complete response following neoadjuvant chemoradiation and esophagectomy for carcinoma of esophagus and gastroesophageal junction
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.27103
Abstract: The aim of this study was to analyze factors associated with pathologic complete response (pCR) following neoadjuvant chemoradiation (NCRT) and esophagectomy for carcinoma of the esophagus (EC) and gastroesophageal junction (GEJ). read more here.
Keywords: following neoadjuvant; complete response; factors associated; neoadjuvant chemoradiation ... See more keywords
Prognostic value of tumour-infiltrating CD8+ lymphocytes in rectal cancer after neoadjuvant chemoradiation: is indoleamine-2,3-dioxygenase (IDO1) a friend or foe?
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-019-02306-y
Abstract: The prognostic value of the local immune phenotype in patients with colorectal cancer has been extensively studied. Neoadjuvant radiotherapy and/or chemotherapy may potentially influence these immune responses. In this study, we examined the prognostic role… read more here.
Keywords: ido1; cd8; prognostic value; neoadjuvant chemoradiation ... See more keywords
Survival analysis in rectal carcinoma after neoadjuvant chemoradiation: various methods with different results
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-017-2861-1
Abstract: PurposeSurvival is an important indicator of outcome quality in rectal carcinoma. The 5-year survival rate is the typical outcome measurement. In patients with neoadjuvant chemoradiation followed by curative surgery, 7 years of follow-up is recommended. Different… read more here.
Keywords: year; neoadjuvant chemoradiation; rate; rectal carcinoma ... See more keywords
Neoadjuvant chemoradiation improves oncologic outcomes in low and mid clinical T3N0 rectal cancers
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-019-03452-6
Abstract: Background Controversial data exists in the current literature in regard to the use of neoadjuvant chemoradiation (nCRT) in patients with clinical T3N0 (cT3N0) rectal cancers, specifically based on location and relation to peritoneal reflection. We… read more here.
Keywords: clinical t3n0; neoadjuvant chemoradiation; rectal cancers; cancer ... See more keywords
Lymphadenectomy and Survival After Neoadjuvant Chemoradiation for Esophageal Adenocarcinoma: Is More Better?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-020-04750-z
Abstract: The purpose of this study was to assess the impact of number of lymph nodes examined on survival in patients with esophageal adenocarcinoma who underwent neoadjuvant chemoradiation. The National Cancer Database was queried for patients… read more here.
Keywords: nodes months; esophageal adenocarcinoma; neoadjuvant chemoradiation; chemoradiation ... See more keywords
Metformin with neoadjuvant chemoradiation to improve pathologic response in rectal cancer: A pilot phase I/II trial
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Translational Radiation Oncology"
DOI: 10.1016/j.ctro.2021.07.001
Abstract: Highlights • A prospective pilot phase I/II study on metformin given concurrently with neoadjuvant chemoradiation (CRT) in non-diabetic rectal cancer patients.• Three patients had a clinical complete response (cCR) and did not have surgical resection.•… read more here.
Keywords: phase; pilot phase; rectal cancer; neoadjuvant chemoradiation ... See more keywords
Neoadjuvant chemoradiation is associated with improved overall survival in older patients with esophageal cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of geriatric oncology"
DOI: 10.1016/j.jgo.2017.08.010
Abstract: OBJECTIVES The aim of this study was to characterize outcomes associated with neoadjuvant chemoradiation prior to esophagectomy, compared to esophagectomy alone, in older patients with esophageal cancer. MATERIALS AND METHODS We conducted an observational cohort… read more here.
Keywords: esophageal cancer; trimodality therapy; neoadjuvant chemoradiation; chemoradiation ... See more keywords
PET-based Treatment Response Assessment for Neoadjuvant Chemoradiation in Pancreatic Adenocarcinoma: An Exploratory Study12
Sign Up to like & getrecommendations! Published in 2018 at "Translational Oncology"
DOI: 10.1016/j.tranon.2018.06.011
Abstract: PURPOSE: Performance of anatomical metrics of Response Evaluation Criteria in Solid Tumors (RECIST1.1) versus Positron Emission Tomography Response Criteria in Solid Tumors (PERCIST1.0) for neoadjuvant chemoradiation (nCR) of pancreatic adenocarcinoma was evaluated based on the… read more here.
Keywords: treatment response; response; pancreatic adenocarcinoma; neoadjuvant chemoradiation ... See more keywords
Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2066767
Abstract: ABSTRACT Patients with pancreatic ductal adenocarcinoma (PDAC) have a grim prognosis despite complete surgical resection and intense systemic therapies. While immunotherapies have been beneficial with many different types of solid tumors, they have almost uniformly… read more here.
Keywords: neoadjuvant chemoradiation; pancreatic ductal; ductal adenocarcinoma; immune microenvironment ... See more keywords