Transcriptomic Analyses of Pretreatment Tumor Biopsy Samples, Response to Neoadjuvant Chemoradiotherapy, and Survival in Patients With Advanced Rectal Cancer
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.52140
Abstract: This case series examines transcriptomic factors associated with outcomes in patients with rectal cancer who received neoadjuvant chemoradiotherapy. read more here.
Keywords: analyses pretreatment; rectal cancer; transcriptomic analyses; neoadjuvant chemoradiotherapy ... See more keywords
Oncological outcome after MRI‐based selection for neoadjuvant chemoradiotherapy in the OCUM Rectal Cancer Trial
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Surgery"
DOI: 10.1002/bjs.10879
Abstract: It is not clear whether all patients with rectal cancer need chemoradiotherapy. A restrictive use of neoadjuvant chemoradiotherapy (nCRT) based on MRI findings for rectal cancer was investigated in this study. read more here.
Keywords: rectal cancer; outcome mri; neoadjuvant chemoradiotherapy; oncological outcome ... See more keywords
CT radiomics identifying non‐responders to neoadjuvant chemoradiotherapy among patients with locally advanced rectal cancer
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DOI: 10.1002/cam4.5086
Abstract: Early detection of non‐response to neoadjuvant chemoradiotherapy (nCRT) for locally advanced colorectal cancer (LARC) remains challenging. We aimed to assess whether pretreatment radiotherapy planning computed tomography (CT) radiomics could distinguish the patients with no response… read more here.
Keywords: locally advanced; identifying non; neoadjuvant chemoradiotherapy; radiomics identifying ... See more keywords
Can we eliminate neoadjuvant chemoradiotherapy in favor of neoadjuvant multiagent chemotherapy for select stage II/III rectal adenocarcinomas: Analysis of the National Cancer Data base
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DOI: 10.1002/cncr.30410
Abstract: Stage II and III rectal cancers have been effectively treated with neoadjuvant chemoradiotherapy (NCRT) followed by definitive resection. Advancements in surgical technique and systemic therapy have prompted investigation of neoadjuvant multiagent chemotherapy (NMAC) regimens with… read more here.
Keywords: stage iii; neoadjuvant chemoradiotherapy; neoadjuvant multiagent; cancer ... See more keywords
LncRNA and mRNA signatures associated with neoadjuvant chemoradiotherapy downstaging effects in rectal cancer
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DOI: 10.1002/jcb.27796
Abstract: Radiotherapy plays a crucial role in combined treatment modality in local advanced rectal cancer (LARC). While neoadjuvant chemoradiotherapy responses were variable in LARC patients, so, it is important to identify genes that closely associated with… read more here.
Keywords: associated neoadjuvant; rectal cancer; neoadjuvant chemoradiotherapy; chemoradiotherapy downstaging ... See more keywords
Prognostic significance of neoadjuvant rectal score in locally advanced rectal cancer after neoadjuvant chemoradiotherapy and construction of a prediction model
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.24907
Abstract: To evaluate the prognostic significance of neoadjuvant rectal (NAR) score after neoadjuvant chemoradiotherapy (nCRT) for locally advanced rectal cancer (LARC), and to develop a nomogram predicting disease‐free survival (DFS). read more here.
Keywords: significance neoadjuvant; neoadjuvant chemoradiotherapy; advanced rectal; locally advanced ... See more keywords
Prediction of local tumor control and recurrence‐free survival in patients with pancreatic cancer undergoing curative resection after neoadjuvant chemoradiotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26854
Abstract: There is little data on the correlation between the reduction in fluorodeoxyglucose positron emission tomography (FDG‐PET) radioactive accumulation and carbohydrate antigen 19‐9 (CA19‐9) levels with pathological tumor responses (PTRs) and prognosis after neoadjuvant chemoradiotherapy (NACRT)… read more here.
Keywords: prediction local; local tumor; patients pancreatic; neoadjuvant chemoradiotherapy ... See more keywords
Clinical benefit of neoadjuvant chemoradiotherapy for the avoidance of pneumonectomy; assessment in 12 consecutive centrally located non-small cell lung cancers
Sign Up to like & getrecommendations! Published in 2017 at "General Thoracic and Cardiovascular Surgery"
DOI: 10.1007/s11748-017-0776-y
Abstract: BackgroundConsidering that pneumonectomy itself is a disease, avoidance of pneumonectomy needs to be deliberated. Herein, we evaluated the role of neoadjuvant chemoradiotherapy for avoidance of pneumonectomy in patients with centrally located locally advanced non-small cell… read more here.
Keywords: centrally located; avoidance pneumonectomy; neoadjuvant chemoradiotherapy; chemoradiotherapy ... See more keywords
Does Neutrophil-to-Lymphocyte Ratio (NLR) Predict Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma?
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DOI: 10.1007/s12029-020-00445-5
Abstract: Background Neoadjuvant chemoradiotherapy (nCRT), followed by surgery, is the current standard of care for patients with locally advanced esophageal squamous cell carcinoma. However, up to 30% of the patients do not respond to nCRT. Hence,… read more here.
Keywords: response; neoadjuvant chemoradiotherapy; patients esophageal; pathologic response ... See more keywords
MLDRL: Multi-loss disentangled representation learning for predicting esophageal cancer response to neoadjuvant chemoradiotherapy using longitudinal CT images.
Sign Up to like & getrecommendations! Published in 2022 at "Medical image analysis"
DOI: 10.1016/j.media.2022.102423
Abstract: Accurate prediction of pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) is essential for clinical precision treatment. However, the existing methods of predicting pCR in esophageal cancer are based on the single stage data, which… read more here.
Keywords: loss disentangled; disentangled representation; esophageal cancer; loss ... See more keywords
Long-Term Results of a Prospective Phase 2 Study on Volume De-Escalation in Neoadjuvant Chemoradiotherapy of Rectal Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Practical radiation oncology"
DOI: 10.1016/j.prro.2020.09.009
Abstract: Abstract Purpose In the current study, we evaluated whether neoadjuvant chemoradiotherapy with reduced treatment volumes due to the exclusion of elective pelvic nodal irradiation is a feasible strategy for selected patients with locally advanced rectal… read more here.
Keywords: rectal cancer; volume; neoadjuvant chemoradiotherapy; study ... See more keywords