Accuracy of Magnetic Resonance Imaging–Guided Biopsy to Verify Breast Cancer Pathologic Complete Response After Neoadjuvant Chemotherapy
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DOI: 10.1001/jamanetworkopen.2020.34045
Abstract: Key Points Question Is the accuracy of magnetic resonance imaging (MRI)–guided biopsy comparable with reference-standard surgical resection for diagnosing pathologic complete response after neoadjuvant chemotherapy in patients with breast cancer? Findings In this pilot nonrandomized… read more here.
Keywords: response neoadjuvant; guided biopsy; accuracy; neoadjuvant chemotherapy ... See more keywords
Neoadjuvant Chemotherapy or Endocrine Therapy for Invasive Ductal Carcinoma of the Breast With High Hormone Receptor Positivity and Human Epidermal Growth Factor Receptor 2 Negativity
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DOI: 10.1001/jamanetworkopen.2021.1785
Abstract: Key Points Question Is neoadjuvant endocrine therapy (NET) an alternative treatment for neoadjuvant chemotherapy (NACT) in patients with invasive ductal carcinoma (IDC) of the breast who have strong hormone receptor (HR) positivity and human epidermal… read more here.
Keywords: endocrine therapy; hormone receptor; invasive ductal; ductal carcinoma ... See more keywords
Association of Adjuvant Chemotherapy in Patients With Resected Pancreatic Adenocarcinoma After Multiagent Neoadjuvant Chemotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.5808
Abstract: Importance The total number of patients with pancreatic ductal adenocarcinoma (PDAC) who receive neoadjuvant chemotherapy (NAC) is increasing. However, the added role of adjuvant chemotherapy (AC) in these patients remains unknown. Objective To evaluate the… read more here.
Keywords: neoadjuvant chemotherapy; group; chemotherapy patients; adjuvant chemotherapy ... See more keywords
Predicting dynamic response to neoadjuvant chemotherapy in breast cancer: a novel metabolomics approach
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13216
Abstract: Neoadjuvant chemotherapy (NACT) outcomes vary according to breast cancer (BC) subtype. Since pathologic complete response is one of the most important target endpoints of NACT, further investigation of NACT outcomes in BC is crucial. Thus,… read more here.
Keywords: breast cancer; neoadjuvant chemotherapy; response;
Neoadjuvant chemotherapy is associated with an altered metabolic profile and increased cancer stemness in patients with pancreatic ductal adenocarcinoma
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DOI: 10.1002/1878-0261.13344
Abstract: The modest clinical benefits of neoadjuvant chemotherapy (NAT) in pancreatic ductal adenocarcinoma (PDAC) are associated with a lack of robust data on treatment‐induced changes in the tumor. To this end, comparative proteomic profiling of tumor… read more here.
Keywords: neoadjuvant chemotherapy; ductal adenocarcinoma; expression; pancreatic ductal ... See more keywords
[18F]Fluorodeoxyglucose PET/CT and prediction of histopathological response to neoadjuvant chemotherapy for adenocarcinoma of the oesophagus and oesophagogastric junction
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DOI: 10.1002/bjs.10712
Abstract: The aim of this prospective study was to assess whether [18F]fluorodeoxyglucose PET can be used to predict histopathological response early in the course of neoadjuvant chemotherapy in patients with adenocarcinoma of the oesophagus and oesophagogastric… read more here.
Keywords: adenocarcinoma oesophagus; 18f fluorodeoxyglucose; fluorodeoxyglucose pet; histopathological response ... See more keywords
Long‐term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer
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DOI: 10.1002/cam4.1104
Abstract: The use of neoadjuvant chemotherapy or radiation for borderline resectable pancreatic adenocarcinoma (BL‐PDAC) is increasing. However, the impact of neoadjuvant chemotherapy and radiation therapy on the outcome of BL‐PDAC remains to be elucidated. We performed… read more here.
Keywords: chemotherapy; upfront chemotherapy; received upfront; neoadjuvant chemotherapy ... See more keywords
From the completion of neoadjuvant chemotherapy to surgery for colorectal cancer liver metastasis: What is the optimal timing?
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DOI: 10.1002/cam4.3283
Abstract: Neoadjuvant chemotherapy (NAC) has been widely performed in the treatment of colorectal cancer liver metastasis (CRLM) patients, but the optimal timing of surgery after NAC is unclear. The aim of this study was to investigate… read more here.
Keywords: surgery; colorectal cancer; cancer liver; neoadjuvant chemotherapy ... See more keywords
Gene signature‐based prediction of triple‐negative breast cancer patient response to Neoadjuvant chemotherapy
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DOI: 10.1002/cam4.3284
Abstract: Neoadjuvant chemotherapy is the current standard of care for large, advanced, and/or inoperable tumors, including triple‐negative breast cancer. Although the clinical benefits of neoadjuvant chemotherapy have been illustrated through numerous clinical trials, more than half… read more here.
Keywords: chemotherapy; neoadjuvant chemotherapy; response; breast cancer ... See more keywords
Circulating immune cell dynamics in patients with triple negative breast cancer treated with neoadjuvant chemotherapy
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DOI: 10.1002/cam4.3358
Abstract: Lymphopenia has been associated with inferior cancer outcomes, but there is limited data in breast cancer. We describe the effects of neoadjuvant chemotherapy on circulating immune cells and its association with pathological complete response (pCR)… read more here.
Keywords: breast cancer; neoadjuvant chemotherapy; circulating immune; cancer ... See more keywords
Utilization of neoadjuvant chemotherapy in high‐risk, node‐negative early breast cancer
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DOI: 10.1002/cam4.4517
Abstract: Controversy exists regarding the optimal sequence of chemotherapy among women with operable node‐negative breast cancers with high‐risk tumor biology. We evaluated national patterns of neoadjuvant chemotherapy (NACT) use among women with early‐stage HER2+, triple‐negative (TNBC),… read more here.
Keywords: breast; neoadjuvant chemotherapy; chemotherapy; node negative ... See more keywords