Lessons in precision oncology from neoadjuvant endocrine therapy trials in ER+ breast cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Breast"
DOI: 10.1016/j.breast.2017.06.039
Abstract: For post-menopausal women with clinical stage II/III estrogen receptor positive (ER+) breast cancer neoadjuvant endocrine therapy (NET) is an under-utilized and low-toxicity alternative to chemotherapy for increasing breast conservation rates. Individual responses to endocrine therapy… read more here.
Keywords: endocrine therapy; breast cancer; therapy; oncology ... See more keywords
Efficacy of Neoadjuvant Endocrine Therapy Versus Neoadjuvant Chemotherapy in ER-positive Breast Cancer: Results From a Prospective Institutional Database.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical breast cancer"
DOI: 10.1016/j.clbc.2019.05.020
Abstract: BACKGROUND Although neoadjuvant chemotherapy (NACT) has been established as a standard for medically fit patients with locally advanced breast cancer, there has been renewed interest in utilizing neoadjuvant endocrine therapy (NET) for women with estrogen… read more here.
Keywords: breast; breast cancer; neoadjuvant chemotherapy; therapy ... See more keywords
Morphological and molecular changes following neoadjuvant endocrine therapy of oestrogen receptor‐positive breast cancer: implications for clinical practice
Sign Up to like & getrecommendations! Published in 2021 at "Histopathology"
DOI: 10.1111/his.14331
Abstract: Neoadjuvant endocrine therapy (NAET) is used in the management of oestrogen receptor (ER)‐positive breast cancer. The optimal method for histological assessment of response and the effect of NAET on the tumour morphology, grade and molecular… read more here.
Keywords: endocrine therapy; breast; breast cancer; oestrogen receptor ... See more keywords
Abstract P5-13-06: Biological and clinical changes after neoadjuvant endocrine treatment: Results in a Spanish cohort of 106 patients
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs19-p5-13-06
Abstract: Background: neoadjuvant endocrine treatment (NET) has demonstrated to be a useful strategy for downstaging luminal breast cancer as well as to deepen into luminal tumors biology. But, in spite of evidence, NET remains as an… read more here.
Keywords: 106 patients; breast; treatment; endocrine treatment ... See more keywords
Similar negative emotional impact on hair loss in neoadjuvant endocrine therapy compared to neoadjuvant chemotherapy in young women with breast cancer from patient reported outcomes.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e19242
Abstract: e19242Background: We aimed to evaluate patient-reported outcomes (PROs) in the NEST phase III trial, in which neoadjuvant endocrine therapy (NET) compared to conventional neoadjuvant chemotherapy (... read more here.
Keywords: endocrine therapy; reported outcomes; patient reported; neoadjuvant chemotherapy ... See more keywords
ASO Author Reflections: Tailoring Axillary Surgery After Neoadjuvant Endocrine Therapy for Breast Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-020-09435-0
Abstract: Although neoadjuvant chemotherapy (NAC) is an excellent approach to downstaging of breast cancer for triple-negative or human epidermal growth factor receptor 2 (HER2)-positive subtypes, a complete response is uncommon in hormone receptor-positive HER2-negative (HR?HER2–) breast… read more here.
Keywords: endocrine therapy; neoadjuvant endocrine; breast; breast cancer ... See more keywords
Neoadjuvant Endocrine Therapy in Breast Cancer Management: State of the Art
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DOI: 10.3390/cancers13040902
Abstract: Simple Summary Over the last ten years, neoadjuvant endocrine therapy (NET) has been increasingly investigated and has gained recognition. NET should not only be used to allow surgery or to improve breast-conserving surgery rates in… read more here.
Keywords: endocrine therapy; breast; net; breast cancer ... See more keywords
The Clinical Impact of Neoadjuvant Endocrine Treatment on Luminal-like Breast Cancers and Its Prognostic Significance: Results from a Single-Institution Prospective Cohort Study
Sign Up to like & getrecommendations! Published in 2022 at "Current Oncology"
DOI: 10.3390/curroncol29040179
Abstract: Purpose: Neoadjuvant endocrine treatment (NET) has become a useful tool for the downstaging of luminal-like breast cancers in postmenopausal patients. It enables us to increase breast- conserving surgery (BCS) rates, provides an opportunity for us… read more here.
Keywords: like breast; treatment; neoadjuvant endocrine; luminal like ... See more keywords
Use of Ultrasound and Ki–67 Proliferation Index to Predict Breast Cancer Tumor Response to Neoadjuvant Endocrine Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Healthcare"
DOI: 10.3390/healthcare11030417
Abstract: Background: Prediction of tumor shrinkage and pattern of treatment response following neoadjuvant endocrine therapy (NET) for estrogen receptor positive (ER+), Her2 negative (Her2–) breast cancers have had limited assessment. We examined if ultrasound (US) and… read more here.
Keywords: response; neoadjuvant endocrine; breast cancer; pattern ... See more keywords
Neoadjuvant Endocrine Therapy in Breast Cancer: Current Knowledge and Future Perspectives
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21103528
Abstract: In locally advanced (LA) breast cancer (BC), neoadjuvant treatments have led to major achievements, which hold particular relevance in HER2-positive and triple-negative BC. Conversely, their role in hormone receptor positive (HR+), hormone epidermal growth factor… read more here.
Keywords: endocrine therapy; neoadjuvant endocrine; breast cancer;