Neoadjuvant Immunotherapy for Patients With Non-Small Cell Lung Cancer-Is a New Era Coming?
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.6898
Abstract: The Viepoint discusses several points regarding whether there is enough data to accept neoadjuvant immunotherapy as a daily practice for patients with operable non–small cell lung cancer. read more here.
Keywords: lung cancer; non small; neoadjuvant immunotherapy; small cell ... See more keywords
Nonoperative Management of dMMR/MSI-H Colorectal Cancer following Neoadjuvant Immunotherapy: A Narrative Review
Sign Up to like & getrecommendations! Published in 2023 at "Clinics in Colon and Rectal Surgery"
DOI: 10.1055/s-0043-1767703
Abstract: Abstract Immunotherapy with PD-1 blockade has achieved a great success in colorectal cancers (CRCs) with high microsatellite instability (MSI-H) and deficient mismatch repair (dMMR), and has become the first-line therapy in metastatic setting. Studies of… read more here.
Keywords: narrative review; immunotherapy; neoadjuvant immunotherapy; msi ... See more keywords
Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic
Sign Up to like & getrecommendations! Published in 2023 at "Oncoimmunology"
DOI: 10.1080/2162402x.2023.2197370
Abstract: ABSTRACT BO-112 is a poly I:C-based viral mimetic that exerts anti-tumor efficacy when intratumorally delivered in mouse models. Intratumoral BO-112 synergizes in mice with systemic anti-PD-1 mAbs and this combination has attained efficacy in PD1-refractory… read more here.
Keywords: intratumoral neoadjuvant; anti tumor; neoadjuvant immunotherapy; tumor efficacy ... See more keywords
Evolutionary patterns and research frontiers in neoadjuvant immunotherapy: a bibliometric analysis.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgery"
DOI: 10.1097/js9.0000000000000492
Abstract: Research has shown that neoadjuvant immunotherapy may provide more significant clinical benefits to cancer patients undergoing surgery than adjuvant therapy. This study examines the development of neoadjuvant immunotherapy research using bibliometric analysis. As of February… read more here.
Keywords: neoadjuvant immunotherapy; immunotherapy; immunotherapy research; bibliometric analysis ... See more keywords
Does major pathological response after neoadjuvant Immunotherapy in resectable non-small-cell lung cancers predict prognosis? a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgery"
DOI: 10.1097/js9.0000000000000496
Abstract: OBJECTIVE Overall survival (OS) is the gold-standard outcome measure for phase 3 trials, but the need for long follow-up period can delay the translation of potentially effective treatment to clinical practice. The validity of Major… read more here.
Keywords: pathological response; non small; immunotherapy; neoadjuvant immunotherapy ... See more keywords
Neoadjuvant immunotherapy versus chemoimmunotherapy in non-small cell lung cancer: A protocol for systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033166
Abstract: Background: Worldwide, lung cancer is the most common cause of cancer morbidity and mortality. Non-small cell lung cancer (NSCLC) accounts for approximately 80 to 85% of all lung cancers. Recently, a few studies have reported… read more here.
Keywords: neoadjuvant immunotherapy; review; meta analysis; chemoimmunotherapy ... See more keywords
Is response evaluation criteria in solid tumors (RECIST) effective in patient selection for radical resection after neoadjuvant immunotherapy with advanced NSCLC?
Sign Up to like & getrecommendations! Published in 2023 at "Thoracic cancer"
DOI: 10.1111/1759-7714.14909
Abstract: BACKGROUND Neoadjuvant immunotherapy combined with chemotherapy has been used to treat locally advanced non-small cell lung cancer (NSCLC). Several systems have been developed for response evaluation. The aim of this study was to evaluate the… read more here.
Keywords: immunotherapy; remission; neoadjuvant immunotherapy; response ... See more keywords
Neoadjuvant immunotherapy of locoregionally advanced solid tumors
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2022-005036
Abstract: Definitive management of locoregionally advanced solid tumors presents a major challenge and often consists of a combination of surgical, radiotherapeutic and systemic therapy approaches. Upfront surgical treatment with or without adjuvant radiotherapy carries the risks… read more here.
Keywords: immunotherapy; therapy; locoregionally advanced; neoadjuvant immunotherapy ... See more keywords
Neoadjuvant Immunotherapy Improves Treatment for Early Resectable Non-Small-Cell Lung Cancer: A Systematic Review and Meta-analysis
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DOI: 10.1155/2022/2085267
Abstract: Objective Immunotherapy has shown better efficacy and less toxicity than chemotherapy in the treatment of non-small-cell lung cancer (NSCLC) at advanced stage. This study evaluates the safety and efficacy of neoadjuvant immunotherapy for resectable NSCLC.… read more here.
Keywords: meta analysis; immunotherapy; neoadjuvant immunotherapy; rate ... See more keywords
Different In Situ Immune Patterns between Primary Tumor and Lymph Node in Non-Small-Cell Lung Cancer: Potential Impact on Neoadjuvant Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/8513747
Abstract: Background Neoadjuvant immunotherapy is promising for locally advanced non-small-cell lung cancer (NSCLC). The in situ immune patterns, as a predictor of PD-1/PD-L1 blockade outcomes, of the primary tumor (PT) and metastatic lymph nodes (mLNs) are… read more here.
Keywords: situ immune; tumor; immune patterns; neoadjuvant immunotherapy ... See more keywords
Neoadjuvant Immunotherapy: Making Strides.
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DOI: 10.1158/2159-8290.cd-nd2020-009
Abstract: Neoadjuvant immune checkpoint inhibition is gaining ground as a treatment strategy for early-stage, operable cancers. The list of potentially responsive tumor types now includes Merkel cell carcinoma; recent findings from an arm of the I-SPY2… read more here.
Keywords: immunotherapy making; neoadjuvant immunotherapy; making strides;