Neoadjuvant chemotherapy in patients undergoing neoadjuvant radiation for trunk and extremity soft tissue sarcoma.
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DOI: 10.1002/jso.27307
Abstract: INTRODUCTION Many patients with high-risk soft tissue sarcoma (STS) develop distant metastases. Meta-analyses suggest that chemotherapy confers a small survival benefit, though few studies focus on neoadjuvant chemotherapy (NCT). There has been more frequent use… read more here.
Keywords: neoadjuvant chemotherapy; neoadjuvant radiation; sarcoma; soft tissue ... See more keywords
Neoadjuvant radiation for clinical T4 colon cancer: A potential improvement to overall survival☆,☆☆
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DOI: 10.1016/j.surg.2018.06.015
Abstract: Background: Resection of T4 colon cancer remains challenging compared to lower T stages. Data on the effect of neoadjuvant radiation to improve resectability and survival are lacking. The purpose of this study is to describe… read more here.
Keywords: neoadjuvant radiation; radiation therapy; colon cancer; radiation ... See more keywords
Impact of long-course neoadjuvant radiation on postoperative low anterior resection syndrome and stoma status in rectal cancer: long-term functional follow-up of a randomized clinical trial
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DOI: 10.1093/bjsopen/zrac127
Abstract: Abstract Background Neoadjuvant radiation has been increasingly associated with postoperative bowel dysfunction, including low anterior resection syndrome (LARS). Although permanent stoma often results from severe bowel dysfunction and significantly impacts quality of life, the presence… read more here.
Keywords: neoadjuvant radiation; stoma; trial; per cent ... See more keywords
Pathologic stage dictates survival after neoadjuvant radiation for rectal cancer
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DOI: 10.18632/oncotarget.26262
Abstract: With the advent of large-scale multicenter data repositories, prognostic data has evolved, causing paradigm shifts in therapeutic approaches and impacting informed discussions with patients and their families. This is especially true with the implementation of… read more here.
Keywords: rectal cancer; neoadjuvant radiation; neoadjuvant therapy; pathologic stage ... See more keywords
Analyzing the impact of neoadjuvant radiation dose on pathologic response and survival outcomes in esophageal and gastroesophageal cancers.
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DOI: 10.21037/jgo.2019.02.18
Abstract: Background The optimal neoadjuvant radiation therapy (RT) dose prior to esophagectomy is unknown. We compared patients receiving lower-dose RT (LD-RT) of 41.4-45 Gy versus those receiving higher-dose RT (HD-RT) of 50-54 Gy. Methods Patients with… read more here.
Keywords: response; analyzing impact; esophageal gastroesophageal; neoadjuvant radiation ... See more keywords