Prognostic analysis of three forms of Ki‐67 in patients with breast cancer with non‐pathological complete response before and after neoadjuvant systemic treatment
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DOI: 10.1002/cam4.5693
Abstract: Patients who do not achieve a pathological complete response (pCR) after neoadjuvant systemic treatment (NST) have a significantly worse prognosis. A reliable predictor of prognosis is required to further subdivide non‐pCR patients. To date, the… read more here.
Keywords: complete response; neoadjuvant systemic; systemic treatment; pathological complete ... See more keywords
Quantitative Apparent Diffusion Coefficients From Peritumoral Regions as Early Predictors of Response to Neoadjuvant Systemic Therapy in Triple‐Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28219
Abstract: Pathologic complete response (pCR) to neoadjuvant systemic therapy (NAST) in triple‐negative breast cancer (TNBC) is a strong predictor of patient survival. Edema in the peritumoral region (PTR) has been reported to be a negative prognostic… read more here.
Keywords: triple negative; breast cancer; neoadjuvant systemic; response ... See more keywords
Neoadjuvant systemic therapy in invasive lobular breast cancer: Is it indicated?
Sign Up to like & getrecommendations! Published in 2018 at "American journal of surgery"
DOI: 10.1016/j.amjsurg.2017.11.011
Abstract: BACKGROUND This study investigated patients with invasive lobular breast carcinoma (ILC) to determine the benefit of neoadjuvant systemic therapy (NAST). METHODS Patients with ILC treated from 2006 to 2015 were identified. Tumor characteristics and treatment… read more here.
Keywords: systemic therapy; invasive lobular; lobular breast; neoadjuvant systemic ... See more keywords
Conservative Management of Positive Axilla After Neoadjuvant Systemic Therapy—The Need for, and Review of, Techniques Used for Lymph Node Localization
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Breast Cancer"
DOI: 10.1016/j.clbc.2018.06.001
Abstract: Abstract Involvement of axillary lymph nodes is an important prognostic factor in relationship to the management of breast cancer. However, the use of neoadjuvant systemic therapy is widespread in the treatment of positive axilla and… read more here.
Keywords: systemic therapy; management; positive axilla; therapy ... See more keywords
Molecular biomarkers to help select neoadjuvant systemic therapy for urothelial carcinoma of the bladder
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Urology"
DOI: 10.1097/mou.0000000000001013
Abstract: Purpose of review In this review, we aimed to summarize the available evidence on pretreatment molecular biomarkers that may help to predict oncologic and pathologic outcomes in patients treated with neoadjuvant systemic therapy (NAST) for… read more here.
Keywords: bladder; molecular biomarkers; neoadjuvant systemic; tumor ... See more keywords
Impact of neoadjuvant systemic chemotherapy followed by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for appendiceal adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Asia-Pacific journal of clinical oncology"
DOI: 10.1111/ajco.13949
Abstract: AIM Peritoneal dissemination of infiltrative appendiceal tumors is a rare and poorly understood phenomenon. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a well-recognized treatment option for selected patients. Neoadjuvant systemic chemotherapy (NAC) has… read more here.
Keywords: surgery; intraperitoneal chemotherapy; neoadjuvant systemic; hyperthermic intraperitoneal ... See more keywords
The Role of Radiotherapy for Patients with Unresectable Locally Advanced Breast Cancer following Neoadjuvant Systemic Therapy
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DOI: 10.1155/2023/5101078
Abstract: Background For locally advanced breast cancer (LABC) patients who remained unresectable after neoadjuvant systemic therapy (NST), radiotherapy (RT) is considered as an approach for tumor downstaging. In this study, we attempted to discuss the value… read more here.
Keywords: locally advanced; pfs; advanced breast; breast cancer ... See more keywords
Innovative Standards in Surgery of the Breast after Neoadjuvant Systemic Therapy
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DOI: 10.1159/000520051
Abstract: Background: The goal of neoadjuvant systemic therapy (NST) in breast cancer is to downstage tumors and downgrade treatment. Indications are constantly evolving. These changes raise practical questions for planning of surgery after NST. Summary: In… read more here.
Keywords: breast; surgery breast; neoadjuvant systemic; surgery ... See more keywords
Survival for head and neck squamous cell carcinoma treated with versus without neoadjuvant systemic therapy: A national propensity score–matched analysis.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.6035
Abstract: 6035 Background: Neoadjuvant systemic therapies, including immunotherapy and chemotherapy, offer a promising approach for treating head and neck squamous cell carcinoma (HNSCC). These therapies aim to reduce tumor burden and enable personalized treatment. While pivotal… read more here.
Keywords: without neoadjuvant; therapy; head neck; immunotherapy ... See more keywords
Surgeon Assessment of the Technical Impact of Neoadjuvant Systemic Therapy on Operable Stage III Melanoma
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DOI: 10.1245/s10434-021-11112-9
Abstract: The effect of neoadjuvant systemic therapies (NST) on technical aspects of operation for resectable stage III melanoma is unknown. Prospective capture of the estimated and actual degree of difficulty of therapeutic lymphadenectomy at presentation and… read more here.
Keywords: iii melanoma; operable stage; stage iii; neoadjuvant systemic ... See more keywords
Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC)
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-021-11236-y
Abstract: Exciting advances in melanoma systemic therapies have presented the opportunity for surgical oncologists and their multidisciplinary colleagues to test the neoadjuvant systemic treatment approach in high-risk, resectable metastatic melanomas. Here we describe the state of… read more here.
Keywords: neoadjuvant systemic; therapy nast; systemic therapy; treatment ... See more keywords