A Dynamic Clinical Calculator for Estimating Conditional Recurrence-Free Survival After Total Neoadjuvant Therapy for Rectal Cancer and Either Surgery or Watch-and-Wait Management
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.33859
Abstract: Key Points Question Can a previously validated clinical calculator be adapted to estimate the risk of rectal cancer recurrence dynamically at different time points for patients who defer surgery after complete response to neoadjuvant therapy?… read more here.
Keywords: free survival; neoadjuvant therapy; recurrence; rectal cancer ... See more keywords
Perioperative Therapy in Early-Stage Lung Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.1940
Abstract: Neoadjuvant Therapy Neoadjuvant therapy refers to any treatment that is given for cancer before surgery, with the goal of making the surgery more likely to be successful and improve the chance of long-term survival. The… read more here.
Keywords: lung cancer; neoadjuvant therapy; early stage; therapy ... See more keywords
Tumor‐Resident Microbiota‐Based Risk Model Predicts Neoadjuvant Therapy Response of Locally Advanced Esophageal Squamous Cell Carcinoma Patients
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DOI: 10.1002/advs.202309742
Abstract: Few predictive biomarkers exist for identifying patients who may benefit from neoadjuvant therapy (NAT). The intratumoral microbial composition is comprehensively profiled to predict the efficacy and prognosis of patients with esophageal squamous cell carcinoma (ESCC)… read more here.
Keywords: esophageal squamous; neoadjuvant therapy; validation; squamous cell ... See more keywords
Targeted axillary dissection after neoadjuvant therapy in breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Surgery"
DOI: 10.1002/bjs.10626
Abstract: The presence of nodal metastases is an important prognostic factor used to direct locoregional and systemic therapies. The use of neoadjuvant therapy has been shown to eliminate nodal metastases in between 40 and 75 per… read more here.
Keywords: seed; per cent; dissection; neoadjuvant therapy ... See more keywords
Long‐Term Outcomes of Neoadjuvant Therapy Versus Upfront Surgery for Resectable Pancreatic Ductal Adenocarcinoma
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DOI: 10.1002/cam4.70363
Abstract: This study aimed to compare the long‐term effects of neoadjuvant therapy and upfront surgery on overall survival (OS) and progression‐free survival (PFS) in patients with resectable pancreatic ductal adenocarcinoma (PDAC). read more here.
Keywords: ductal adenocarcinoma; long term; neoadjuvant therapy; upfront surgery ... See more keywords
A practical framework for the targeted use of total neoadjuvant therapy for rectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34149
Abstract: Total neoadjuvant therapy (TNT) for rectal cancer is the preoperative delivery of radiation or chemoradiotherapy as well as systemic chemotherapy for the purpose of improving treatment completion rates and decreasing toxicity, maximizing the primary tumor… read more here.
Keywords: neoadjuvant therapy; cancer practical; total neoadjuvant; rectal cancer ... See more keywords
Total neoadjuvant therapy in rectal cancer: The FOREST protocol, a patient‐centered approach that clusters two cohorts with different outcomes
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Cancer"
DOI: 10.1002/ijc.70126
Abstract: Rectal cancer treatment has evolved toward individualized strategies that emphasize organ preservation and tailored therapeutic approaches. The FOREST protocol combines total neoadjuvant therapy (TNT), early response evaluation, and prehabilitation within a comprehensive framework designed to… read more here.
Keywords: cancer; protocol; neoadjuvant therapy; rectal cancer ... See more keywords
Total neoadjuvant therapy with six versus four cycles of CAPOX in locally advanced rectal cancer: A real-world study.
Sign Up to like & getrecommendations! Published in 2025 at "International journal of cancer"
DOI: 10.1002/ijc.70151
Abstract: The optimal number of systemic chemotherapies for total neoadjuvant therapy (TNT) in locally advanced rectal cancer (LARC) is controversial. This retrospective study, conducted at Fujian Medical University Union Hospital from January 2018 to April 2024,… read more here.
Keywords: cycles capox; cancer; capox group; neoadjuvant therapy ... See more keywords
Impact of neoadjuvant therapy on postoperative outcomes after pancreaticoduodenectomy
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DOI: 10.1002/jso.25183
Abstract: Surgical resection provides the only potentially curative treatment of pancreatic cancer. Neoadjuvant chemotherapy and/or radiation (NAT) is used to downstage patients with borderline resectable tumors. The objective of this study was to examine the postoperative… read more here.
Keywords: impact neoadjuvant; outcomes pancreaticoduodenectomy; neoadjuvant therapy; postoperative outcomes ... See more keywords
Impact of neoadjuvant therapy followed by laparoscopic radical gastrectomy with D2 lymph node dissection in Western population: A multi-institutional propensity score-matched study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of surgical oncology"
DOI: 10.1002/jso.26657
Abstract: BACKGROUND AND OBJECTIVES In the setting of a minimally invasive approach, we aimed to compare short and long-term postoperative outcomes of patients treated with neoadjuvant therapy (NAT) + surgery or upfront surgery in Western population. METHODS All… read more here.
Keywords: node dissection; gastrectomy lymph; western population; propensity score ... See more keywords
Reply to: “Impact of neoadjuvant therapy followed by laparoscopic radical gastrectomy with D2 lymph node dissection in Western population: a multi‐institutional propensity score matched study”
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26733
Abstract: Dear Editor, We appreciate with interest the paper written by Bracale et al. entitled “Impact of neoadjuvant therapy followed by laparoscopic radical gastrectomy with D2 lymph node dissection in Western population: a multi‐institutional propensity score… read more here.
Keywords: laparoscopic radical; neoadjuvant therapy; impact neoadjuvant; gastrectomy ... See more keywords