Mutation-Derived Neoantigens for Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01856
Abstract: Mutation-derived neoantigens distinguish tumor from normal cells. T cells can sense the HLA-presented mutations, recognize tumor cells as non-self and destroy them. Therapeutically, immunotherapy antibodies can increase the virulence of the immune system by increasing… read more here.
Keywords: mutation derived; derived neoantigens; mutated proteins; neoantigens cancer ... See more keywords
Identification of Neoantigens in Cancer Cells as Targets for Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052594
Abstract: The clinical benefits of immune checkpoint blockage (ICB) therapy have been widely reported. In patients with cancer, researchers have demonstrated the clinical potential of antitumor cytotoxic T cells that can be reinvigorated or enhanced by… read more here.
Keywords: cancer cells; identification neoantigens; cells targets; neoantigens cancer ... See more keywords