Translating the application of transforming growth factor‐β1, chondroitinase‐ABC, and lysyl oxidase‐like 2 for mechanically robust tissue‐engineered human neocartilage
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2791
Abstract: Strategies to overcome the limited availability of human articular chondrocytes and their tendency to dedifferentiate during expansion are required to advance their clinical use and to engineer functional cartilage on par with native articular cartilage.… read more here.
Keywords: transforming growth; human neocartilage; treatment; neocartilage ... See more keywords
Stiffness- and Bioactive Factor-Mediated Protection of Self-Assembled Cartilage against Macrophage Challenge in a Novel Co-Culture System
Sign Up to like & getrecommendations! Published in 2022 at "Cartilage"
DOI: 10.1177/19476035221081466
Abstract: Objective: Tissue-engineered cartilage implants must withstand the potential inflammatory and joint loading environment for successful long-term repair of defects. The work’s objectives were to develop a novel, direct cartilage-macrophage co-culture system and to characterize interactions… read more here.
Keywords: culture; neocartilage; cartilage; factor ... See more keywords