Modular Approach to pseudo-Neoclerodanes as Designer κ-Opioid Ligands.
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DOI: 10.1021/acs.orglett.7b02684
Abstract: Informed by previous semisynthetic work on salvinorin A, a modular total synthesis has been developed capable of producing novel compounds targeting the κ-opioid receptor. The strategy has permitted the deliberate simplification and introduction of functionality… read more here.
Keywords: designer opioid; modular approach; neoclerodanes designer; approach pseudo ... See more keywords