Vomocytosis of Cryptococcus neoformans cells from murine, bone marrow-derived dendritic cells
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DOI: 10.1371/journal.pone.0280692
Abstract: Cryptococcus neoformans (CN) cells survive within the acidic phagolysosome of macrophages for extended times, then escape without impacting the viability of the host cell via a phenomenon that has been coined ‘vomocytosis’. Through this mechanism,… read more here.
Keywords: vomocytosis cryptococcus; neoformans cells; vomocytosis; dendritic cells ... See more keywords
Behind the Curtain: In Silico and In Vitro Experiments Brought to Light New Insights into the Anticryptococcal Action of Synthetic Peptides
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DOI: 10.3390/antibiotics12010153
Abstract: Cryptococcus neoformans is the pathogen responsible for cryptococcal pneumonia and meningitis, mainly affecting patients with suppressed immune systems. We have previously revealed the mechanism of anticryptococcal action of synthetic antimicrobial peptides (SAMPs). In this study,… read more here.
Keywords: action synthetic; behind curtain; neoformans cells; action ... See more keywords
Novel ABC Transporter Associated with Fluconazole Resistance in Aging of Cryptococcus neoformans
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DOI: 10.3390/jof8070677
Abstract: Cryptococcus neoformans causes meningoencephalitis in immunocompromised individuals, which is treated with fluconazole (FLC) monotherapy when resources are limited. This can lead to azole resistance, which can be mediated by overexpression of ABC transporters, a class… read more here.
Keywords: afr3; neoformans cells; novel abc; resistance ... See more keywords