MLST-Based Population Genetic Analysis in a Global Context Reveals Clonality amongst Cryptococcus neoformans var. grubii VNI Isolates from HIV Patients in Southeastern Brazil
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DOI: 10.1371/journal.pntd.0005223
Abstract: Cryptococcosis is an important fungal infection in immunocompromised individuals, especially those infected with HIV. In Brazil, despite the free availability of antiretroviral therapy (ART) in the public health system, the mortality rate due to Cryptococcus… read more here.
Keywords: cryptococcus neoformans; neoformans var; population genetic; var grubii ... See more keywords
Comparative genomics of Cryptococcus neoformans var. grubii associated with meningitis in HIV infected and uninfected patients in Vietnam
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DOI: 10.1371/journal.pntd.0005628
Abstract: The vast burden of cryptococcal meningitis occurs in immunosuppressed patients, driven by HIV, and is caused by Cryptococcus neoformans var. grubii. We previously reported cryptococcal meningitis in Vietnam arising atypically in HIV uninfected, apparently immunocompetent… read more here.
Keywords: meningitis; cryptococcus neoformans; neoformans var; var grubii ... See more keywords
In Vitro Antifungal Activity of Chimeric Peptides Derived from Bovine Lactoferricin and Buforin II against Cryptococcus neoformans var. grubii
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DOI: 10.3390/antibiotics11121819
Abstract: Cryptococcosis is associated with high rates of morbidity and mortality. The limited number of antifungal agents, their toxicity, and the difficulty of these molecules in crossing the blood–brain barrier have made the exploration of new… read more here.
Keywords: antifungal activity; bovine lactoferricin; var grubii; activity ... See more keywords
Gene expression profiles of ERG11, MDR1 and AFR1 in Cryptococcus neoformans var.grubbi from HIV patients
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DOI: 10.7705/biomedica.6519
Abstract: Introduction: Fluconazole is the most used antifungal drug for prevention and treatment of Cryptococcus spp. infections, the etiological agent of cryptococcosis. Resistance to fluconazole among Cryptococcus neoformans isolates can lead to treatment failure and generate… read more here.
Keywords: expression profiles; resistance; neoformans var; cryptococcus neoformans ... See more keywords