MicroRNA-302a promotes neointimal formation following carotid artery injury in mice by targeting PHLPP2 thus increasing Akt signaling
Sign Up to like & getrecommendations! Published in 2020 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-020-0440-4
Abstract: The excessive proliferation and migration of smooth muscle cells (SMCs) play an important role in restenosis following percutaneous coronary interventions. MicroRNAs are able to target various genes and involved in the regulation of diverse cellular… read more here.
Keywords: mir 302a; neointimal formation; carotid artery; proliferation ... See more keywords
CFTR Suppresses Neointimal Formation Through Attenuating Proliferation and Migration of Aortic Smooth Muscle Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001257
Abstract: Supplemental Digital Content is Available in the Text. Abstract: Cystic fibrosis transmembrane conductance regulator (CFTR) plays important roles in arterial functions and the fate of cells. To further understand its function in vascular remodeling, we… read more here.
Keywords: formation; proliferation migration; neointimal formation; cftr ... See more keywords
Thymoquinone suppresses platelet‐derived growth factor‐BB–induced vascular smooth muscle cell proliferation, migration and neointimal formation
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DOI: 10.1111/jcmm.14738
Abstract: The excessive proliferation and migration of vascular smooth muscle cells (VSMCs) are mainly responsible for vascular occlusion diseases, such as pulmonary arterial hypertension and restenosis. Our previous study demonstrated thymoquinone (TQ) attenuated monocrotaline‐induced pulmonary arterial… read more here.
Keywords: migration; neointimal formation; smooth muscle; proliferation ... See more keywords
Contribution of Vascular Cells to Neointimal Formation
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DOI: 10.1371/journal.pone.0168914
Abstract: The de-differentiation and proliferation of smooth muscle cells (SMCs) are widely accepted as the major contributor to vascular remodeling. However, recent studies indicate that vascular stem cells (VSCs) also play an important role, but their… read more here.
Keywords: neointimal formation; vascular cells; contribution; cre rosa ... See more keywords
Ant-Neointimal Formation Effects of SLC6A6 in Preventing Vascular Smooth Muscle Cell Proliferation and Migration via Wnt/β-Catenin Signaling
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DOI: 10.3390/ijms24033018
Abstract: Vascular smooth muscle cells (VSMCs) play an important role in the pathogenesis of vascular remolding, such as atherosclerosis and restenosis. Solute carrier family 6 member 6 (SLC6A6) is a transmembrane transporter that maintains a variety… read more here.
Keywords: wnt catenin; proliferation migration; neointimal formation;
The New Weapon to Inhibit Proliferation and Migration of Smooth Muscle Cell in Neointimal Formation
Sign Up to like & getrecommendations! Published in 2020 at "Korean Circulation Journal"
DOI: 10.4070/kcj.2020.0197
Abstract: https://e-kcj.org Neointimal formation known as thickening of the intima is initiated by mechanical damage to the arterial endothelium, which then promotes local inflammatory cell recruitment, chemokine production and vascular smooth muscle cell (VSMC) migration to… read more here.
Keywords: proliferation migration; neointimal formation; migration; smooth muscle ... See more keywords