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   Articles with "neointimal hyperplasia" as a keyword



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Chemokine‐like factor 1 (CKLF1) aggravates neointimal hyperplasia through activating the NF‐κB /VCAM‐1 pathway

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recommendations! Published in 2020 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12942

Abstract: Neointimal hyperplasia (NIH) is a complicated inflammatory process contributing to vascular restenosis. The present study aimed to explore whether chemokine‐like factor 1 (CKLF1) aggravates NIH via the nuclear factor‐kappa B (NF‐κB)/vascular cell adhesion molecule‐1 (VCAM‐1)… read more here.

Keywords: vcam pathway; cklf1; like factor; chemokine like ... See more keywords
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Neointimal hyperplasia in the inferior vena cava of adenine-induced chronic kidney disease rats with aortocaval fistulas

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recommendations! Published in 2020 at "Clinical and Experimental Nephrology"

DOI: 10.1007/s10157-020-01927-3

Abstract: The failure of autologous arteriovenous fistulas (AVFs) occurs primarily due to stenosis in the anastomotic site, which is mainly related to the development of neointimal hyperplasia (NIH). Therefore, we conducted a study to establish a… read more here.

Keywords: chronic kidney; adenine induced; aortocaval fistulas; induced chronic ... See more keywords
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Semaphorin-3A protects against neointimal hyperplasia after vascular injury

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recommendations! Published in 2019 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2018.12.023

Abstract: BACKGROUND Neointimal hyperplasia is a prominent pathological event during in-stent restenosis. Phenotype switching of vascular smooth muscle cells (VSMCs) from a differentiated/contractile to a dedifferentiated/synthetic phenotype, accompanied by migration and proliferation of VSMCs play an… read more here.

Keywords: hyperplasia vascular; sema3a; vascular injury; neointimal hyperplasia ... See more keywords

Wedelolactone, a plant coumarin, prevents vascular smooth muscle cell proliferation and injury-induced neointimal hyperplasia through Akt and AMPK signaling

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recommendations! Published in 2017 at "Experimental Gerontology"

DOI: 10.1016/j.exger.2017.06.011

Abstract: Abstract Wedelolactone (WDL) is a natural compound derived from Chinese herbal medicine Eclipta prostrate L, and has been reported to exhibit various effects potentially beneficial for human health. However, the possible preventive effects of WDL… read more here.

Keywords: akt ampk; proliferation; wedelolactone; neointimal hyperplasia ... See more keywords
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Cholinergic anti-inflammatory pathway inhibits neointimal hyperplasia by suppressing inflammation and oxidative stress

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recommendations! Published in 2018 at "Redox Biology"

DOI: 10.1016/j.redox.2017.11.013

Abstract: Neointimal hyperplasia as a consequence of vascular injury is aggravated by inflammatory reaction and oxidative stress. The α7 nicotinic acetylcholine receptor (α7nAChR) is a orchestrator of cholinergic anti-inflammatory pathway (CAP), which refers to a physiological… read more here.

Keywords: 7nachr mice; inflammation; neointimal hyperplasia; injury ... See more keywords
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PARP1 deficiency protects against hyperglycemia-induced neointimal hyperplasia by upregulating TFPI2 activity in diabetic mice

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recommendations! Published in 2021 at "Redox Biology"

DOI: 10.1016/j.redox.2021.102084

Abstract: Diabetes mellitus (DM) promotes neointimal hyperplasia, characterized by dysregulated proliferation and accumulation of vascular smooth muscle cells (VSMCs), leading to occlusive disorders, such as atherosclerosis and stenosis. Poly (ADP-ribose) polymerase 1 (PARP1), reported as a… read more here.

Keywords: induced neointimal; proliferation; hyperglycemia induced; parp1 ... See more keywords
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Catalpol Ameliorates Neointimal Hyperplasia in Diabetic Rats.

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recommendations! Published in 2019 at "Planta medica"

DOI: 10.1055/a-0818-3689

Abstract: Catalpol, an iridoid glycoside, is an isolated natural product of Rehmannia glutinosa, which has been reported to have antidiabetic properties. This study investigated the vascular protective effects of catalpol in hyperglycemic rats with balloon-injured carotid… read more here.

Keywords: monocyte chemoattractant; chemoattractant protein; neointimal hyperplasia;
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O16: TARGETING THE LOX-1 SCAVENGER RECEPTOR ATTENUATES ATHEROSCLEROSIS AND NEOINTIMAL HYPERPLASIA IN APO-E NULL TRANSGENIC MICE

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recommendations! Published in 2021 at "British Journal of Surgery"

DOI: 10.1093/bjs/znab117.016

Abstract: The clinical consequences of atherosclerosis and post-procedure neointimal hyperplasia (NIH) represent a significant proportion of the vascular surgeon's workload. Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) is a class E scavenger receptor expressed in endothelial… read more here.

Keywords: scavenger receptor; mice; neointimal hyperplasia; lox ... See more keywords
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BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein Synthesis

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recommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2021/5986260

Abstract: The rate of ribosome biogenesis plays a vital role in cell cycle progression and proliferation and is strongly connected with coronary restenosis and atherosclerosis. Blocking of proliferation 1 (BOP1) has been found as an evolutionarily… read more here.

Keywords: protein; bop1 knockdown; proliferation; neointimal hyperplasia ... See more keywords
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MFN2 Prevents Neointimal Hyperplasia in Vein Grafts via Destabilizing PFK1

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recommendations! Published in 2022 at "Circulation Research"

DOI: 10.1161/circresaha.122.320846

Abstract: Background: Mechanical forces play crucial roles in neointimal hyperplasia after vein grafting; yet, our understanding of their influences on vascular smooth muscle cell (VSMC) activation remains rudimentary. Methods: A cuff mouse model was used to… read more here.

Keywords: pfk1; stretch; neointimal hyperplasia; vein grafts ... See more keywords
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Microbiota control acute arterial inflammation and neointimal hyperplasia development after arterial injury

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recommendations! Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0208426

Abstract: Background The microbiome has a functional role in a number of inflammatory processes and disease states. While neointimal hyperplasia development has been linked to inflammation, a direct role of the microbiota in neointimal hyperplasia has… read more here.

Keywords: inflammation; hyperplasia development; mice; neointimal hyperplasia ... See more keywords