Structural analysis of neomycin B and kanamycin A binding Aminoglycosides Modifying Enzymes (AME) and bacterial ribosomal RNA
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DOI: 10.1002/minf.202300339
Abstract: Aminoglycosides are crucial antibiotics facing challenges from bacterial resistance. This study addresses the importance of aminoglycoside modifying enzymes in the context of escalating resistance. Drawing upon over two decades of structural data in the Protein… read more here.
Keywords: neomycin kanamycin; structural analysis; modifying enzymes; analysis neomycin ... See more keywords