Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic
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DOI: 10.1016/j.redox.2020.101718
Abstract: Sex as a biological variable plays a critical role both during lung development and in modulating postnatal hyperoxic lung injury and repair. The molecular mechanisms behind these sex-specific differences need to be elucidated. Our objective… read more here.
Keywords: response hyperoxia; sex; neonatal lung; lung ... See more keywords
Effect of sex chromosomes versus hormones in neonatal lung injury
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DOI: 10.1172/jci.insight.146863
Abstract: The main mechanisms underlying sexually dimorphic outcomes in neonatal lung injury are unknown. We tested the hypothesis that hormone- or sex chromosome–mediated mechanisms interact with hyperoxia exposure to impact injury and repair in the neonatal… read more here.
Keywords: related pathways; pathways enriched; neonatal lung; sex ... See more keywords
Thyroid hormone modulates hyperoxic neonatal lung injury and mitochondrial function.
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DOI: 10.1172/jci.insight.160697
Abstract: Mitochondrial dysfunction at birth predicts bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants. Recently, nebulized thyroid hormone (TH), given as triiodothyronine (T3) was noted to decrease pulmonary fibrosis in adult animals through improved… read more here.
Keywords: lung; mitochondrial function; neonatal lung; lung injury ... See more keywords
The Outcome- or Cost-Effectiveness Analysis of LUS-Based Care or CXR-Based Care of Neonatal Lung Diseases: The Clinical Practice Evidence from a Level â…¢ NICU in China
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DOI: 10.3390/diagnostics12112790
Abstract: Objective: To compare the effect of managing neonatal lung disease with lung ultrasound (LUS) or chest X-ray (CXR) monitoring on health outcomes and cost-effectiveness. Methods: The data obtained from the NICU of the Beijing Chaoyang… read more here.
Keywords: lus based; neonatal lung; based care; lung ... See more keywords