Clinical and pathologic implications of extending the spectrum of maternal autoantibodies reactive with ribonucleoproteins associated with cutaneous and now cardiac neonatal lupus from SSA/Ro and SSB/La to U1RNP.
Sign Up to like & getrecommendations! Published in 2017 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2017.07.013
Abstract: While the relationship between maternal connective tissue diseases and neonatal rashes was described in the 1960s and congenital heart block in the 1970s, the "culprit" antibody reactivity to the SSA/Ro-SSB/La ribonucleoprotein complex was not identified… read more here.
Keywords: neonatal lupus; ssa; clinical pathologic; ssa ssb ... See more keywords
Cutaneous Sequelae in Neonatal Lupus: A Retrospective Cohort Study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2019.09.083
Abstract: BACKGROUND Cutaneous eruptions in neonatal lupus erythematosus (NLE) are thought to be self-resolving. Limited literature suggests cutaneous changes may persist. OBJECTIVE To characterize cutaneous residua in NLE, and identify predictors for their development. METHODS A… read more here.
Keywords: retrospective cohort; neonatal lupus; cohort study; cutaneous sequelae ... See more keywords
Gut dysbiosis and the clinical spectrum in anti-Ro positive mothers of children with neonatal lupus
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DOI: 10.1080/19490976.2022.2081474
Abstract: ABSTRACT Anti-SSA/Ro antibodies, while strongly linked to fetal cardiac injury and neonatal rash, can associate with a spectrum of disease in the mother, ranging from completely asymptomatic to overt Systemic Lupus Erythematosus (SLE) or Sjögren’s… read more here.
Keywords: children neonatal; spectrum; neonatal lupus; clinical spectrum ... See more keywords
Complete heart block in neonatal lupus: a forgotten cause of fetal bradycardia
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DOI: 10.1136/bcr-2021-246747
Abstract: The most common cause of congenital heart block (CHB) is neonatal lupus, an acquired autoimmune disease caused by transplacental transfer of maternal antibodies to the fetus. A full-term female neonate was admitted to neonatal intensive… read more here.
Keywords: neonatal lupus; fetal bradycardia; block; heart block ... See more keywords
Lupus Pneumonitis: Case Report of a Rare Manifestation of Neonatal Lupus
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DOI: 10.1177/23247096221077815
Abstract: Neonatal lupus is a rare entity, secondary to placental transfer of antibodies from mothers with immune-mediated conditions. While pulmonary involvement is common in lupus, its incidence in neonates is extremely rare, with very few cases… read more here.
Keywords: lupus pneumonitis; neonatal lupus; pneumonitis case; case ... See more keywords
Neonatal lupus with left bundle branch block and cardiomyopathy: a case report
Sign Up to like & getrecommendations! Published in 2020 at "BMC Cardiovascular Disorders"
DOI: 10.1186/s12872-020-01637-4
Abstract: Background Cardiac manifestations of neonatal lupus include an array of structural and conduction abnormalities due to placental transference of maternal anti-SSA/Ro and anti-SSB/La autoantibodies. Late-onset neonatal lupus cardiomyopathies, occurring outside the neonatal period, is an… read more here.
Keywords: bundle branch; neonatal lupus; case; branch block ... See more keywords
Geoepidemiology and clinical characteristics of neonatal lupus erythematosus: a systematic literature review of individual patients’ data
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DOI: 10.3906/sag-1910-39
Abstract: Background/aim Neonatal lupus erythematosus (NLE) is an autoimmune syndrome caused by transplacental transmission of maternal autoantibodies, often with devastating consequences. The objective of this systematic literature review was to analyze the demographic data, geoepidemiology, clinical,… read more here.
Keywords: neonatal lupus; systematic literature; lupus erythematosus; literature review ... See more keywords
Methylprednisolone Pulse Therapy Can Be Life-Saving in Neonatal Lupus Erythematous: A Case Report
Sign Up to like & getrecommendations! Published in 2017 at "Iranian Journal of Pediatrics"
DOI: 10.5812/ijp.9004
Abstract: Introduction: Neonatal lupus erythematous (NLE) is a neonatal autoimmune disease, due to passage of maternal autoantibodies against Ro/SS-A, La/SS-B, and U1-ribonucleoprotein, with multi organ involvement. Although the clinical manifestations of NLE include cutaneous, cardiac, hematologic,… read more here.
Keywords: lupus erythematous; neonatal lupus; case; clinical manifestations ... See more keywords