RTA‐408 protects against propofol‐induced cognitive impairment in neonatal mice via the activation of Nrf2 and the inhibition of NF‐κB p65 nuclear translocation
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1918
Abstract: To explore the effect of RTA‐408 on the propofol‐induced cognitive impairment of neonatal mice via regulating Nrf2 and NF‐κB p65 nuclear translocation. read more here.
Keywords: rta 408; propofol induced; induced cognitive; cognitive impairment ... See more keywords
Whole-brain mapping of neuronal activity evoked by maternal separation in neonatal mice: An association with ultrasound vocalization.
Sign Up to like & getrecommendations! Published in 2023 at "Neuropsychopharmacology reports"
DOI: 10.1002/npr2.12337
Abstract: Neonatal mice emit ultrasonic vocalizations (USVs) when separated from their mothers. Since the USVs attract their mothers' attention and trigger maternal retrieval, they are considered to serve as social signals for communication. We have modeled… read more here.
Keywords: usv production; neonatal mice; brain; neuronal activity ... See more keywords
Effects of antibiotics on the developing enamel in neonatal mice.
Sign Up to like & getrecommendations! Published in 2021 at "European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry"
DOI: 10.1007/s40368-021-00677-4
Abstract: PURPOSE Identifying factors causing Molar-Incisor Hypomineralization (MIH) is an ongoing challenge. Preterm infants, routinely treated with antibiotics in cases of suspected sepsis, are more commonly affected by dental developmental defects. This study aimed to investigate… read more here.
Keywords: developing enamel; neonatal mice; antibiotics developing; mice ... See more keywords
Leflunomide induces NAD(P)H quinone dehydrogenase 1 enzyme via the aryl hydrocarbon receptor in neonatal mice.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.02.051
Abstract: Aryl hydrocarbon receptor (AhR) has been increasingly recognized to play a crucial role in normal physiological homeostasis. Additionally, disrupted AhR signaling leads to several pathological states in the lung and liver. AhR activation transcriptionally induces… read more here.
Keywords: leflunomide; ahr; aryl hydrocarbon; enzyme ... See more keywords
Hyperoxia exposure disrupts adrenomedullin signaling in newborn mice: Implications for lung development in premature infants.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.04.112
Abstract: Hyperoxia contributes to the development of bronchopulmonary dysplasia (BPD), a chronic lung disease of human infants that is characterized by disrupted lung angiogenesis. Adrenomedullin (AM) is a multifunctional peptide with angiogenic and vasoprotective properties. AM… read more here.
Keywords: hyperoxia exposure; neonatal mice; mice; lung development ... See more keywords
Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103+ dendritic cell populations following respiratory infection
Sign Up to like & getrecommendations! Published in 2018 at "Mucosal immunology"
DOI: 10.1038/mi.2017.28
Abstract: The CD103+ subset of lung-migratory dendritic cells (DCs) plays an important role in the generation of CD8+ T cell responses following respiratory infection. Here, we demonstrate that the dependence on CD103+ DCs for stimulation of… read more here.
Keywords: dcs; cd103; respiratory infection; neonatal mice ... See more keywords
Neuropathology in Neonatal Mice After Experimental Coxsackievirus B2 Infection Using a Prototype Strain, Ohio-1.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlz124
Abstract: Coxsackievirus B (CVB) causes severe morbidity and mortality in neonates and is sometimes associated with severe brain damage resulting from acute severe viral encephalomyelitis. However, the neuropathology of CVB infection remains unclear. A prototype strain… read more here.
Keywords: neuropathology; infection; neonatal mice; prototype strain ... See more keywords
Cochleovestibular gene transfer in neonatal mice by canalostomy
Sign Up to like & getrecommendations! Published in 2017 at "NeuroReport"
DOI: 10.1097/wnr.0000000000000827
Abstract: Impairments of the inner ear result in sensorineural hearing loss and vestibular dysfunction in humans. A large proportion of these disorders are congenital, and involve both auditory and vestibular systems. Therefore, genetic interventions to correct… read more here.
Keywords: inner ear; canalostomy; neonatal mice; gene transfer ... See more keywords
Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aax3387
Abstract: A different route of administering GM-CSF may selectively manipulate tissue-resident macrophages to therapeutic benefit. Pneumonia poses profound health threats to preterm infants. Alveolar macrophages (AMs) eliminate inhaled pathogens while maintaining surfactant homeostasis. As AM development… read more here.
Keywords: inhaled csf; bacterial pneumonia; neonatal mice; csf neonatal ... See more keywords
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1330928
Abstract: Objective Our previous results showed that icariin (ICA) could inhibit apoptosis and provide neuroprotection against hypoxic-ischemic brain damage (HIBD) in neonatal mice, but the specific mechanism of its neuroprotective effect remains unknown. This study aims… read more here.
Keywords: neonatal mice; apoptosis; ica pretreatment; mice ... See more keywords
Dextran sodium sulfate (DSS) induces necrotizing enterocolitis-like lesions in neonatal mice
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0182732
Abstract: Background Necrotizing enterocolitis (NEC) is an inflammatory bowel disease of preterm human newborns with yet unresolved etiology. An established neonatal murine model for NEC employs oral administration of lipopolysaccharides (LPS) combined with hypoxia/hypothermia. In adult… read more here.
Keywords: dextran sodium; neonatal mice; necrotizing enterocolitis; mice ... See more keywords