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Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.08.001
Abstract: Excessive prenatal opioid exposure may lead to the development of Neonatal Opioid Withdrawal Syndrome (NOWS). RNA-seq was done on 64 formalin-fixed paraffin-embedded placental tissue samples from 32 mothers with opioid use disorder, with newborns with…
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Keywords:
opioid withdrawal;
withdrawal syndrome;
opioid use;
neonatal opioid ... See more keywords
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Published in 2021 at "Journal of Perinatology"
DOI: 10.1038/s41372-021-01206-3
Abstract: Neonates born to mothers taking opioids during pregnancy are at risk for neonatal opioid withdrawal syndrome (NOWS), for which there is no recognized standard approach to care. Nonpharmacologic treatment is typically used as a first-line…
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Keywords:
opioid withdrawal;
withdrawal syndrome;
use buprenorphine;
neonatal opioid ... See more keywords
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Published in 2022 at "American journal of perinatology"
DOI: 10.1055/a-1877-9291
Abstract: BACKGROUND Infants with neonatal opioid withdrawal syndrome (NOWS) have disrupted neurobehavior that requires hospitalization and treatment. OBJECTIVE To evaluate EEG abnormalities using amplitude integrated EEG (aEEG) in NOWS. DESIGN/METHODS Eighteen term born infants with NOWS…
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Keywords:
withdrawal;
neonatal opioid;
integrated eeg;
amplitude integrated ... See more keywords
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Published in 2019 at "American journal of perinatology"
DOI: 10.1055/s-0039-1693716
Abstract: OBJECTIVE Our cost-effectiveness analysis investigated rooming-in versus not rooming-in to determine optimal management of neonates with neonatal opioid withdrawal (NOW). STUDY DESIGN A decision-analytic model was constructed using TreeAge to compare rooming-in versus not rooming-in…
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Keywords:
opioid withdrawal;
effectiveness analysis;
cost;
neonatal opioid ... See more keywords
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Published in 2020 at "Substance Abuse"
DOI: 10.1080/08897077.2020.1784360
Abstract: Abstract Background The opioid epidemic in the United States continues to threaten public health. As a result of this crisis, neonatal opioid withdrawal syndrome (NOWS) has risen exponentially and requires a multitude of non-pharmacologic treatments…
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Keywords:
acupressure;
opioid withdrawal;
withdrawal syndrome;
treatment ... See more keywords
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Published in 2019 at "Journal of Addiction Medicine"
DOI: 10.1097/adm.0000000000000484
Abstract: OBJECTIVE The objective of this study was to compare short-term outcomes of neonatal opioid withdrawal syndrome (NOWS) treatment in infants exposed in-utero to opioids and selective serotonin reuptake inhibitors (SSRIs) or opioids alone. METHODS This…
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Keywords:
selective serotonin;
withdrawal;
neonatal opioid;
opioid withdrawal ... See more keywords
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Published in 2023 at "Advances in Neonatal Care"
DOI: 10.1097/anc.0000000000001056
Abstract: Background: While a growing body of literature has established the role of human milk as a mechanism of protection in the formation of the infant gut microbiome, it remains unclear the extent to which this…
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Keywords:
neonatal opioid;
opioid withdrawal;
infant gut;
gut microbiome ... See more keywords
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Published in 2019 at "Addiction biology"
DOI: 10.1111/adb.12806
Abstract: Opioid use among pregnant women is a growing public health concern in the United States. Infants exposed to opioids in utero are at risk of exhibiting neonatal opioid withdrawal syndrome (NOWS). The biological mechanisms underlying…
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Keywords:
oprm1 snp;
exposure;
neonatal opioid;
opioid exposure ... See more keywords
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Published in 2023 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-067883
Abstract: Introduction Rates of neonatal opioid withdrawal syndrome (NOWS) have paralleled the rise of opioid use during pregnancy. While short-term phenotypic symptoms of NOWS are well defined, molecular implications and long-term effects are not well understood.…
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Keywords:
review;
neonatal opioid;
scoping review;
opioid withdrawal ... See more keywords
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Published in 2023 at "Public health reports"
DOI: 10.1177/00333549231162375
Abstract: OBJECTIVE The opioid epidemic has led to a surge in diagnoses of neonatal opioid withdrawal syndrome (NOWS). Many states track the incidence of NOWS by using the P96.1 International Classification of Diseases, Tenth Revision, Clinical…
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Keywords:
withdrawal;
incidence;
p04;
neonatal opioid ... See more keywords
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Published in 2022 at "Journal of neonatal-perinatal medicine"
DOI: 10.3233/npm-220989
Abstract: BACKGROUND Infants with in-utero exposure to opioids are at risk Neonatal Opioid Withdrawal Syndrome (NOWS) and non-pharmacological methods of care, like swaddling, quiet ambient environment are routinely recommended but are not systematically studied. We hypothesized…
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Keywords:
massage;
whole body;
methodology;
neonatal opioid ... See more keywords