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Published in 2020 at "Anesthesiology"
DOI: 10.1097/aln.0000000000003165
Abstract: Background: Recent studies suggest that adult-specific treatment options for fibrinogen replacement during bleeding may be less effective in neonates. This is likely due to structural and functional differences found in the fibrin network between adults…
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Keywords:
microscopy;
adult;
porcine human;
neonatal porcine ... See more keywords
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Published in 2018 at "Transplantation"
DOI: 10.1097/tp.0000000000002354
Abstract: Background There is a strong rationale to pursue the use of neonatal porcine islets (NPIs) as an unlimited source of islets for clinical xenotransplantation. Because NPIs are composed of immature insulin producing beta (ß) cells…
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Keywords:
neonatal porcine;
vitro differentiation;
differentiation;
cell ... See more keywords
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Published in 2019 at "Xenotransplantation"
DOI: 10.1111/xen.12546
Abstract: Neonatal pigs have the potential to provide an inexhaustible source of islets for the treatment of type 1 diabetes. However, the immunological barriers to islet xenotransplantation still need to be overcome. A better understanding of…
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Keywords:
neonatal porcine;
early immune;
rejection;
porcine islet ... See more keywords
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Published in 2020 at "Xenotransplantation"
DOI: 10.1111/xen.12581
Abstract: Cell transplantation has been widely recognized as a curative treatment strategy for variety of diseases including type I diabetes (T1D). Broader patient inclusion for this therapeutic option is restricted by a limited supply of healthy…
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Keywords:
neonatal porcine;
porcine islets;
transplantation;
stem cells ... See more keywords
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Published in 2022 at "Xenotransplantation"
DOI: 10.1111/xen.12739
Abstract: Some clinical trials have shown the usefulness of stem cell therapy for diabetic foot ulcers. However, the donor supply is limited, and the process is time consuming and expensive. This study assessed the therapeutic effects…
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Keywords:
neonatal porcine;
bone marrow;
marrow derived;
xenotransplantation ... See more keywords
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Published in 2017 at "BMC Veterinary Research"
DOI: 10.1186/s12917-017-1239-5
Abstract: BackgroundThe aim of this study was to investigate whether the syndrome New Neonatal Porcine Diarrhoea Syndrome (NNPDS) is associated with a viral aetiology. Four well-managed herds experiencing neonatal diarrhoea and suspected to be affected by…
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Keywords:
neonatal porcine;
diarrhoea;
porcine;
diarrhoea syndrome ... See more keywords
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Published in 2022 at "Polymers"
DOI: 10.3390/polym14061120
Abstract: The subcutaneous space is currently being pursued as an alternative transplant site for ß-cell replacement therapies due to its retrievability, minimally invasive procedure and potential for graft imaging. However, implantation of ß-cells into an unmodified…
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Keywords:
porcine islets;
function;
neonatal porcine;
plga ... See more keywords